2021
DOI: 10.1016/j.ijscr.2021.105931
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Surgical debridement, maggot therapy, negative pressure wound therapy, and silver foam dressing revive hope for patients with diabetic foot ulcer: A case report

Abstract: Introduction and importance Diabetic foot ulcers (DFUs), as one of the most debilitating complications of diabetes, can lead to amputation. Treatment and management of d DFUs are among the most critical challenges for the patients and their families. Case presentation The present case report is of a 63-year-old man with a 5-year history of uncontrolled type 2 diabetes who has had DFU for the past three years on three sites of the left external ankle in the form of two d… Show more

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Cited by 37 publications
(34 citation statements)
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“…At present, the therapeutic strategies for TBI include hyperbaric oxygen therapy (HBOT), hyperventilation and hypertonic therapy, noninvasive brain stimulation, drug therapy, and biological therapy [ 27 ]. Most importantly, the combinational use of novel biological reagents (genes and stem cells) and pharmacological intervention preparations can decrease the complications and mortality of TBI [ 28 ].…”
Section: Tbimentioning
confidence: 99%
“…At present, the therapeutic strategies for TBI include hyperbaric oxygen therapy (HBOT), hyperventilation and hypertonic therapy, noninvasive brain stimulation, drug therapy, and biological therapy [ 27 ]. Most importantly, the combinational use of novel biological reagents (genes and stem cells) and pharmacological intervention preparations can decrease the complications and mortality of TBI [ 28 ].…”
Section: Tbimentioning
confidence: 99%
“…Consequently, MMP-9 is regarded as a novel target for the treatment of chronic diabetic wounds [ 15 ]. In addition, another factor that affects the healing of diabetic wounds is the irregular shape of wounds after removing the necrotic tissues; traditional clinical dressings give rise to a higher risk of infection due to their quite unfitting shape of the irregular wounds [ [16] , [17] , [18] , [19] ]. Overall, it is necessary to develop a wound dressing that fully adapts to the wound shape as well as regulates the level of MMP-9 and glucose, thereby accelerating the healing of chronic diabetic wounds.…”
Section: Introductionmentioning
confidence: 99%
“…Innovative treatment methods are needed for wound management [7] , [8] . Using tilapia fish skin (TFS) is one of the new strategies that have been used in wound management [9] .…”
Section: Introductionmentioning
confidence: 99%