“…In addition, alcohol has a direct effect on mitochondrial metabolism and causes premature aging of mtDNA [ 16 ]. A mechanism for reducing the number and activity of β-adrenergic receptors seems significant, thus reducing the lipolytic processes and increasing lipogenesis [ 14 , 17 ]. Demyelinating alcohol-associated disorders of the peripheral nervous system may have an effect on β-adrenergic stimulation [ 14 ].…”