2006
DOI: 10.1590/s0004-27302006000500021 View full text |Buy / Rent full text
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Christianne T.S. Leal,
Paulo G.S. Lacativa,
Elaine M.S. Gomes
et al.

Abstract: Brown tumors are relatively uncommon but they are serious complications of renal osteodystrophy. We describe a 31-year-old woman with end-stage renal disease who had undergone hemodialysis for nine years and developed severe secondary hyperparathyroidism and a maxilla brown tumor despite increasing doses of oral calcitriol and calcium carbonate. The fast increase of the right maxillary bone tumor led to indication of parathyroidectomy (PTx). Despite normalization of serum PTH there was a slow regression of the… Show more

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“…[32][33][34][35] These symptoms are typically referred for treatment to specialties of maxillofacial surgery, oral surgery, reconstructive and plastic surgery, ENT, ophthalmology, and dentistry. The lesions from OFC and BT are not painful and often produce symptoms, depending on the location of facial asymmetry, oral mass, nasal obstruction, sinusitis, progressive visual disturbances, proptosis, chewing diffi-culties, hearing abnormalities, and airway obstruction in the pediatric population.…”
Section: Discussionmentioning
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“…[32][33][34][35] These symptoms are typically referred for treatment to specialties of maxillofacial surgery, oral surgery, reconstructive and plastic surgery, ENT, ophthalmology, and dentistry. The lesions from OFC and BT are not painful and often produce symptoms, depending on the location of facial asymmetry, oral mass, nasal obstruction, sinusitis, progressive visual disturbances, proptosis, chewing diffi-culties, hearing abnormalities, and airway obstruction in the pediatric population.…”
Section: Discussionmentioning
“…Radiographically, they appear as well demarcated monolocular or multilocular osteolytic lesions. In the mandible, the cortical bone is expanded and thinned (12,14). Brown tumors of the jaws occasionally result in root resorption and loss of the lamina dura and may present as a space occupying mass in the sinus (17).…”
Section: Discussionmentioning
“…Actually they represent a reparative cellular process rather than a true neoplasia (6, 12). They are known to occur only in the setting of HPT, and are considered the most pathognomonic skeletal changes that accompany this disease (12). At skeletal sites excess parathyroid hormone can lead to a condition called osteitis fibrosa cystica.…”
Section: Introductionmentioning
“…Leal et al. reported a slow regression of a maxillary BT after 2 years of follow‐up, requiring local excision . Therefore, an early diagnosis and a timely subtotal PTX in a medically resistant sHPT are an optimal option to control the growth of the bony lesion and to avoid further weakening of bone structure and consequent increased risk of fractures, compression of contiguous structures, deformities, and functional alteration of other involved areas of the skeleton …”
Section: Discussionmentioning