2012
DOI: 10.1111/j.1542-4758.2012.00695.x
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Abstract: Brown tumors (BTs) are relatively uncommon but they are serious complications of renal osteodystrophy. The objective of this study was to analyze the clinical, biological, and radiological characteristics of 16 patients with BTs provoked by secondary hyperparathyroidism (sHPT) and its response to the decrease in parathyroid hormone levels after parathyroidectomy (PTX). The management of that uncommon condition was also reviewed. We conducted a retrospective study including 16 end-stage renal disease patients w… Show more

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Cited by 10 publications
(10 citation statements)
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References 29 publications
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“…29 Secondary hyperparathyroidism is a frequent complication of CRF, and brown tumours are seen in 1.50-1.75% of patients with secondary hyperparathyroidism. 30 These tumours are also associated with CRF and are being reported with increasing frequency. 25,30,31 Brown tumours result from the destruction of local bone occurring especially in regions where bone resorption is particularly rapid with haemorrhage and reparative granulation tissue containing giant multinucleated cells replace the normal marrow content.…”
Section: Discussionmentioning
confidence: 99%
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“…29 Secondary hyperparathyroidism is a frequent complication of CRF, and brown tumours are seen in 1.50-1.75% of patients with secondary hyperparathyroidism. 30 These tumours are also associated with CRF and are being reported with increasing frequency. 25,30,31 Brown tumours result from the destruction of local bone occurring especially in regions where bone resorption is particularly rapid with haemorrhage and reparative granulation tissue containing giant multinucleated cells replace the normal marrow content.…”
Section: Discussionmentioning
confidence: 99%
“…30 These tumours are also associated with CRF and are being reported with increasing frequency. 25,30,31 Brown tumours result from the destruction of local bone occurring especially in regions where bone resorption is particularly rapid with haemorrhage and reparative granulation tissue containing giant multinucleated cells replace the normal marrow content. 30 The majority of brown tumour cases reported the jaws as the main sites of occurrence.…”
Section: Discussionmentioning
confidence: 99%
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“…Thirty-six cases from three articles were excluded from the analysis as they did not have information on the variables we sought to collect as they only provided group patient data and not individual patient data. 14,27,28 Our total sample consisted of 99 articles (see supplementary material). These articles resulted in 127 cases that were included in the analysis (including our case, see supplementary material).…”
Section: Resultsmentioning
confidence: 99%
“…28 The reasons for increased life expectancy included increased attention to dose of dialysis delivered, changes in dialysis equipment, including a shift from cellulosic to synthetic HD membranes, improved connection devices for PD, and better management of anemia through the wide use of rhEPO and parenteral iron. The young African-American woman had developed ESRD from focal segmental glomerulosclerosis (FSGS) and had HD for 5 years.…”
Section: Discussionmentioning
confidence: 99%