Surgery for carcinoma of the breast in women over 70 years of age

Amsterdam, E. A.; Birkenfeld, Shlomo; Gilad, Adi; Krispin, M

doi:10.1002/jso.2930350308

Cited by 36 publications

(7 citation statements)

References 3 publications

(3 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Older patients in good health can tolerate expeditious mastectomy with an operative risk similar to that of younger patients.i'' Hunt et al 2 l showed that the average mortality rate in older patients undergoing mastectomy is less than 1%. A similar finding was reported by Amsterdam et aJ.. 22 In our study, there were no operative mortalities, and the rate of morbidity (8.4%) was acceptable, mainly related to shortterm wound complications.…”

Section: Younger Patientssupporting

confidence: 92%

Breast Cancer in Women 70 Years of Age or Older

Masetti

Antinori

Terribile

et al. 1996

J American Geriatrics Society

View full text Add to dashboard Cite

show abstract

Section: Younger Patientssupporting

confidence: 92%

Breast Cancer in Women 70 Years of Age or Older

Masetti

Antinori

Terribile

et al. 1996

J American Geriatrics Society

View full text Add to dashboard Cite

show abstract

“…Nevertheless, it remains clear that invasive breast cancer in any age group requires adequate treatment in order to achieve maximum survival and, furthermore, when women 70 years or over are so treated, there is no increase in morbidity and the 5 year survival rate is similar to women under 70 years of age (Amsterdam et al, 1987). The findings in this paper do not suggest that breast cancer in the elderly warrants less aggressive treatment than that for the young.…”

Section: Discussionmentioning

confidence: 59%

Histopathology of breast cancer in relation to age

Fisher

Egan²,

Smith³

et al. 1997

Br J Cancer

150

View full text Add to dashboard Cite

Summary Histological reports of 1869 consecutive women with invasive breast cancer have been reviewed to determine whether histological features of the tumours were related to the patients' age. The patients, treated between 1983 and 1992, were divided into four groups, based on age. There were 148 aged < 39 years, 355 aged [40][41][42][43][44][45][46][47][48][49] years, 984 aged 50-69 years and 382 aged 70 years or more. The most outstanding finding was the increase in incidence of grade IlIl infiltrating ductal carcinoma in those aged < 39 years (P< 0.0001). Certain tumour types, in particular lobular, were reported more frequently in the oldest age group. Additionally, there was a significant reduction of axillary lymph node metastases, vascular invasion and lymphoplasmacytic stromal reaction with increasing age, all of which were independent of tumour grade. These data suggest that there may be age-related changes in the histology of breast cancer and, in some cases, less aggressive features in the elderly. However, as the life expectancy of women over the age of 70 may be many years, treatment should be based on histological prognostic features of the primary tumour rather than age alone.Keywords: breast cancer; histology; age; tumour grade; axillary nodes There are reports indicating that breast cancer has a relatively unfavourable prognosis in young women (Jacquemier et al, 1985;Rosen et al, 1985;Rochefordiere et al, 1993), but is a disease of good prognosis among the elderly (Rosen et al, 1985). However, others have suggested that age does not influence the behaviour of the disease (Schaefer et al, 1984). Relatively few comparative studies of histological features of breast cancer in the young and old have been conducted. It has been reported that there is a significantly lower mean age for patients with medullary carcinoma, while lobular and mucoid carcinomas are relatively more frequent in the elderly (Rosen et al, 1985). Intracystic papillary carcinoma is also found more frequently in older women (Carter et al, 1983). In addition, it has been suggested that younger women have more aggressive high-grade tumours than the elderly (Jacquemier et al, 1985;Rosen et al, 1985).The aim of the present investigation was to review a large series of patients with invasive breast cancer and to analyse a variety of histopathological findings in relation to age, in order to determine whether there were any indications of less or more aggressive features in different age groups. PATIENTS AND METHODSThe study comprised 1869 women with invasive breast cancer who were treated consecutively at the Breast Unit, Guy's Hospital, in the 10-year period 1983-1992. The patients were divided into four age groups, < 39 years, 40-49 years, 50-69 years and > 70 years. These age groups were selected for the following reasons.The cut-off age for young women has ranged from 30-45 years in previous studies (Jacquemier et al, 1985;Rosen et al, 1985;Lee et al, 1992 Correspondence to: IS Fentiman reasonable size, which was compatible with ...

show abstract

“…It is imperative to weigh the benefits and risks of the method of treatments with consideration of the sequelae of the aging processes in elderly patient with Stage IV breast carcinoma [3,4]. Elazar et al revealed the results of study that elderly women with breast cancer should be treated by surgical methods that offer the best chance of cure regardless of the patient's age.…”

Section: Discussionmentioning

confidence: 99%

“…However, elderly women should be generally treated in a more conservative manner than younger women. In advanced stage of cancer, simple mastectomy is done for palliative purposes [4]. Associated illnesses were of particular concern because of the impact on surgical risks as well as the quality of life in elderly patient.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life after Palliative Mastectomy for Stage IV Breast Cancer in Elderly

Sm¹

2014

Surgery

View full text Add to dashboard Cite

Advance breast cancer still becomes a debate among surgeons either to act aggressively in view of the survival outcome. However the problem may arise from the disease progress which can be complicated by sepsis due to infection, severe bleeding, foul odour and sensation of heaviness. The decision will be more complicated if it occurs among geriatric patients. Here we presented a case of neglected right breast cancer which was treated late when it occupied the whole breast. The histopathological results revealed Poorly Differentiated Infiltrating Ductal Carcinoma and CT Scan showed liver and lung metastases (Stage IV). Palliative mastectomy was done to prevent complication such as infection and sepsis, bleeding and to reduce the sensation of heaviness. The discussion focused on the role of mastectomy to improve quality of life in elderly with advance breast cancer. They are highly distressed by the loss of independent self-care and thus, can slide into depression. Comprehensive rehabilitation services should be provided to alleviate and improve their quality of life [9]. Quality of Life after Palliative Mastectomy for Stage IV Breast Cancer in Elderly

show abstract

Surgery for carcinoma of the breast in women over 70 years of age

Cited by 36 publications

References 3 publications

Breast Cancer in Women 70 Years of Age or Older

Breast Cancer in Women 70 Years of Age or Older

Histopathology of breast cancer in relation to age

Quality of Life after Palliative Mastectomy for Stage IV Breast Cancer in Elderly

Contact Info

Product

Resources

About