Surface Properties and Biocompatibility of Acid-etched Titanium

Iwaya, Yukari; Machigashira, Miho; Kanbara, Kenji; Miyamoto, Mari; Noguchi, Kazuyuki; Izumi, Yuichi; Ban, Seiji

doi:10.4012/dmj.27.415

Cited by 71 publications

(60 citation statements)

References 37 publications

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“…Our data are also in agreement with findings showing that acid etching of grit blasted titanium had no substantial impact on proliferation and collagen production of MC3T3-E1 cells 22) or on osteogenic differentiation of MG63 cells 21) . Thus, the present results provide additional support for the view that modifications of already grit blasted surfaces, even if they might have an impact on the process of osseointegration in vivo, do not necessarily have an impact on cell behavior in vitro.…”

Section: Discussionsupporting

confidence: 82%

Acid and alkali etching of grit blasted zirconia: Impact on adhesion and osteogenic differentiation of MG63 cells in vitro

et al. 2012

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There is a need for evaluating zirconia surface modifications and their potential impact on the biological response of osteogenic cells. Grit blasted zirconia discs were either left untreated or underwent acid or alkaline etching. Adhesion and osteogenic differentiation of MG63 cells was determined after one week of culture. The macro-scaled roughness of the grit blasted zirconia discs, independent of the surface treatment, was within a narrow range and only slightly smoother than titanium discs. However, the alkaline-and acid-etching led to an increase of the micro-roughness of the surface. The surface modifications had no effect on cell spreading and did not cause significant change in the expression of differentiation markers. Thus, in this respective setting, morphologic changes observed upon treatment of grit blasted zirconia discs with acid or alkaline do not translate into changes in MG63 cell adhesion or differentiation and are comparable to findings with anodized titanium discs.

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Section: Discussionsupporting

confidence: 82%

Acid and alkali etching of grit blasted zirconia: Impact on adhesion and osteogenic differentiation of MG63 cells in vitro

et al. 2012

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“…Microspheres of diameter in the range 10-540 µm are typically accelerated toward the surface to be treated, using a compressed air or nitrogen blow. Most used grid materials include corundum (Al 2 O 3 ) [9,10], silicon carbide (SiC) [11], titania (TiO 2 ) [12], hydroxyapatite (HA) [13], zirconia (ZrO 2 ) [14], silica (SiO 2 ) [15] and aluminum powders [15]. The main effect of sandblasting is to change the morphology of the treated surface, substantially increasing its roughness.…”

Section: Surface Treatmentsmentioning

confidence: 99%

Surface Treatments and Functional Coatings for Biocompatibility Improvement and Bacterial Adhesion Reduction in Dental Implantology

et al. 2016

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Surface modification of dental implants is a key process in the production of these medical devices, and especially titanium implants used in the dental practice are commonly subjected to surface modification processes before their clinical use. A wide range of treatments, such as sand blasting, acid etching, plasma etching, plasma spray deposition, sputtering deposition and cathodic arc deposition, have been studied over the years in order to improve the performance of dental implants. Improving or accelerating the osseointegration process is usually the main goal of these surface processes, but the improvement of biocompatibility and the prevention of bacterial adhesion are also of considerable importance. In this review, we report on the research of the recent years in the field of surface treatments and coatings deposition for the improvement of dental implants performance, with a main focus on the osseointegration acceleration, the reduction of bacterial adhesion and the improvement of biocompatibility.

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“…Several studies have reported that acid treatment modifies the wettability of titanium surfaces [13,23]. In wettability test, the contact angle of acid treatment was significantly higher than non-treated and alkali treatment.…”

Section: -2 Corrosion Depthmentioning

confidence: 94%

“…Chemical treatments corrode the titanium surface, making it rough, extremely hydrophilic, and suitable for bone formation [23]. The corrosion depth is not a serious problem for solid titanium materials such as implant fixtures.…”

Section: Introductionmentioning

confidence: 99%

Investigation of Effective Modification Treatments for Thin Titanium Membranes

Kobatake¹,

Doi²,

Oki³

et al. 2017

Preprint

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Titanium membranes are used for guided bone regeneration in implant therapy. However, as a bioinert material, titanium does not have the ability to accelerate bone formation. Various titanium surface treatments to confer bioactivity have been demonstrated; however, there are concerns about the influence of chemical treatments on the corrosion of thin titanium membranes. This study investigated the influence of surface modifications on the structure of thin titanium membranes. Titanium membranes of 20 µm thickness were treated with acid or alkali solutions, and we evaluated their surface structure, wettability, corrosion depth, and mechanical strength compared to non-treated membranes. Alkali-treated thin titanium membranes displayed the formation of nanoscale pore structures on their surfaces, enhanced hydrophilicity, and less corrosion depth compared with acid-treated membranes. Furthermore, the tensile strength of alkali-treated membranes was comparable to non-treated membranes. These results suggest that alkali treatment is an appropriate surface modification method for thin titanium membranes.

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Surface Properties and Biocompatibility of Acid-etched Titanium

Cited by 71 publications

References 37 publications

Acid and alkali etching of grit blasted zirconia: Impact on adhesion and osteogenic differentiation of MG63 cells in vitro

Acid and alkali etching of grit blasted zirconia: Impact on adhesion and osteogenic differentiation of MG63 cells in vitro

Surface Treatments and Functional Coatings for Biocompatibility Improvement and Bacterial Adhesion Reduction in Dental Implantology

Investigation of Effective Modification Treatments for Thin Titanium Membranes

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