Surface-enhanced Raman spectroscopy for comparison of serum samples of typhoid and tuberculosis patients of different stages

Advances in the fabrication of potential nanomaterials for diagnosis and effective treatment of tuberculosis

“…Ag NPs are capable of differentiating between bacteria, such as tuberculosis and typhoid, which have similar symptoms. 80 However, an SPR sensor, which is based on an Ag layer of 65 nm, a barium titanate (BaTiO 3 ) layer of 9 nm, and two graphene layers, is also applied for detecting tuberculosis. Increasing the thickness of the Ag layer improved the transfer of incident light energy to the surface plasmon, leading to efficient excitation of the surface plasmon.…”

Recent advances in antibiotic resistance diagnosis using SERS: focus on the “Big 5” challenges

“…Due to these challenges, several SERS diagnostic applications have been evolved for the early detection of TB biomarkers. 123,124 For example, Porter's group developed multiple SERS based sandwich immunoassays demonstrating the importance of TB sample pre-treatment in enhancing the sensitivity of TB biomarkers detection in human serum samples. [125][126][127][128] For example, in the detection of the TB biomarker, mannose-capped lipoarabinomannan (ManLAM), in pre-treated human serum samples.…”

“…Due to these challenges, several SERS diagnostic applications have been evolved for the early detection of TB biomarkers. 123,124…”