Advances in the fabrication of potential nanomaterials for diagnosis and effective treatment of tuberculosis

El-Shabasy, Rehan M.; Zahran, Moustafa; Ibrahim, Ahmed H.; Maghraby, Yasmin R.; Nayel, Mohamed

doi:10.1039/d3ma00720k

Mater. Adv.

2024

DOI: 10.1039/d3ma00720k

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Advances in the fabrication of potential nanomaterials for diagnosis and effective treatment of tuberculosis

Rehan M. El-Shabasy,

Moustafa Zahran,

Ahmed H. Ibrahim

et al.

Abstract: This review sheds light on the novel nanomaterials required for rapid and clear diagnosis of tuberculosis, and compiles and discusses their limitations and future prospects.

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Clinically Relevant Metallic Nanoparticles in Tuberculosis Diagnosis and Therapy

Akinnawo,

Dube

2024

Advanced Therapeutics

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Globally a significant burden of tuberculosis (TB) is faced, which is difficult to eradicate due to patients' non‐adherence, and drug‐resistant strains that are spreading at an alarming rate. Novel approaches are required to improve diagnosis and treatment. Metallic nanoparticles (MNPs) have demonstrated potential as sensor probes and in combination therapy, which combines MNPs with antimycobacterial drugs to develop new treatment and theranostic approaches. To strengthen the theoretical foundation toward the clinical application of TB nanomedicine, this review focuses on the properties and effectiveness of therapeutically relevant MNPs. It also elaborates on their antimycobacterial mechanisms. This review aims to analyze the body of literature on the topic, pinpoint important empirical findings, and identify knowledge gaps that can provide a basis for future research endeavors and translation of the technologies. Current data suggest that MNPs are potential systems for efficient diagnosis and treatment although additional pre‐clinical and clinical research is needed to bring these technologies to the clinic.

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Clinically Relevant Metallic Nanoparticles in Tuberculosis Diagnosis and Therapy

Akinnawo,

Dube

2024

Advanced Therapeutics

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Advances in the fabrication of potential nanomaterials for diagnosis and effective treatment of tuberculosis

Abstract: This review sheds light on the novel nanomaterials required for rapid and clear diagnosis of tuberculosis, and compiles and discusses their limitations and future prospects.

Cited by 1 publication

References 93 publications

Clinically Relevant Metallic Nanoparticles in Tuberculosis Diagnosis and Therapy

Clinically Relevant Metallic Nanoparticles in Tuberculosis Diagnosis and Therapy

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