Surface binding of aflatoxin B1 by Saccharomyces cerevisiae strains with potential decontaminating abilities in indigenous fermented foods

Shetty, Prathapkumar Halady; Hald, Birthe; Jespersen, Lene

doi:10.1016/j.ijfoodmicro.2006.07.013

Cited by 190 publications

(145 citation statements)

References 27 publications

Supporting

Mentioning

130

Contrasting

Unclassified

Order By: Relevance

“…The proteins and glucans provide numerous easily accessible binding sites with different binding mechanisms such as hydrogen bonding, ionic or hydrophobic interactions. The binding of aflatoxin to yeast cell surface has been attributed to cell wall glucans (30).…”

Section: Discussionmentioning

confidence: 99%

“…Zeolites (12,16), bentonites (7,11,26), and yeast/esterified glucomannan (1,4,6,15) were opted for because of their effect on reducing aflatoxin absorption from the gastrointestinal tract. Some studies have showed that the best method for decontamination is biological degradation by yeast and yeast components, which can remove aflatoxin under mild conditions, without using harmful chemicals or causing noticeable losses in nutritive value and palatableness of the feed (21,30).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Assessment of serum biochemical parameters and pathological changes in broilers with chronic aflatoxicosis fed glucomannan-containing yeast product (Mycosorb) and sodium bentonite

Azizpour

Moghadam

2015

Bulletin of the Veterinary Institute in Pulawy

View full text Add to dashboard Cite

The purpose of this study was to evaluate the efficacy of yeast glucomannan (YG) and sodium bentonite (SB) in reducing the toxicity in broilers fed a diet naturally contaminated with aflatoxin. Three hundred 7-day-old Ross 308 strain broilers were chosen and randomly assigned to 10 dietary treatments. Serum biochemical parameters and pathological changes in the liver were investigated at 42 d of age. Chickens fed a diet containing 250 ppb of aflatoxin displayed a decrease in uric acid, cholesterol, and triglycerides, and an increase in serum activities of AST and ALT when compared to control group. There were considerable gross and histopathological hepatic lesions (P < 0.05) in the form of small to moderate hydropic and/or fatty degeneration, bile duct hyperplasia, periportal fibrosis, cells infiltration, and congestion, in chickens fed the 250 ppb aflatoxincontaining diet. The addition of YG and SB to the aflatoxin-containing diet partially reduced the negative effects of aflatoxin. The 0.1% YG supplementation to the aflatoxin-contaminated diet significantly prevented the pathological effect of aflatoxin on serum biochemical parameters and liver, and was found to be more effective than other treatments.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Assessment of serum biochemical parameters and pathological changes in broilers with chronic aflatoxicosis fed glucomannan-containing yeast product (Mycosorb) and sodium bentonite

Azizpour

Moghadam

2015

Bulletin of the Veterinary Institute in Pulawy

View full text Add to dashboard Cite

show abstract

“…Recently, an increase in the research connected with mycotoxin detoxification by microorganisms has been observed. Several studies showed that some bacteria, moulds, and yeasts, for example Lactobacillus acidophilus, Bifidobacterium animalis, Oenococcus oeni, Aspergillus niger, A. carbonarius, A. fumigatus, Saccharomyces cerevisiae, and Kloeckera apiculata are able to detoxify mycotoxins [19][20][21][22][23][24][25].…”

Section: Introductionmentioning

confidence: 99%

“…Recent investigations demonstrate that Saccharomyces cerevisiae strains are able to remove OTA from plant raw material during fermentation of wine, beer, or sourdough [23,[26][27][28][29]. Some authors reported decreasing ochratoxin levels during winemaking [26,27,[30][31][32].…”

Section: Introductionmentioning

confidence: 99%

Removal of ochratoxin A by wine Saccharomyces cerevisiae strains

Piotrowska

Nowak

Czyżowska

2013

Eur Food Res Technol

View full text Add to dashboard Cite

The aim of this work was to examine two wine strains of Saccharomyces cerevisiae (Syrena LOCK 0201 and Malaga LOCK 0173 strains) and thermally inactivated biomass of bakery yeast (BS strain) for their ability to remove ochratoxin A (OTA) from model YPG, white grape GM, and blackcurrant BM media. The media was initially contaminated by 1 lg/mL OTA. The influence of OTA on yeast growth parameters, kinetic of fermentation, and amount of ethanol, glycerol, and acids were determined. It was found that both yeast strains were able to decrease the toxin amount in YPG, GM, and BM media. Strain Malaga LOCK 0173 was able to remove 82.8 and 10.7 % ochratoxin A from grape and blackcurrant medium, respectively. In case of Syrena LOCK 0201 strain, the OTA reduction was higher: 85.1 % for grape and 65.2 % for blackcurrant media. From 54.1 to 64.4 % of initial ochratoxin A concentration was removed after the contaminated wine treatment by thermally inactivated baker's yeast strain (BS) cells. The elongation of lag phase in contaminated YPG medium compared on toxin-free medium was noted. In white grape and blackcurrant medium, the differences between the final cell number, fermentation rate, moreover the ethanol, glycerol, and acids production in the medium with OTA and the control were not statistically significant. The results showed that the application of selected strains of yeasts in winemaking involving raw material contaminated with OTA might reduce the toxin contamination as well as the health risk related to human exposure to this toxin. Moreover, the application of heat-inactivated yeast's biomass for toxin adsorption gives new possibilities in oenology.

show abstract

“…Shetty et al (63) found that the ability of S. cerevisiae to bind aflatoxin B 1 was strain specific with 7 strains binding 10-20%, 8 strains binding 20-40% and 3 strains binding more than 40% of the added aflatoxin B 1 . El-Nezami et al (62), testing the ability of L. rhamnosus to bind aflatoxin B 1 in vivo, also noted the specificity of the strains with one strain reducing absorption by 74% (strain GG) while another (strain LC-705) reduced absorption by only 37%.…”

Section: Mycotoxin Bindingmentioning

confidence: 99%