Supramolecular design of CO2-responsive lipid nanomaterials

CO2-Responsive Water-Soluble Conjugated Polymers as a Multifunctional Fluorescent Probe for Bioimaging Applications

“…In recent years, gas-responsive materials have attracted widespread attention and research due to their unique physical and chemical properties. − Carbon dioxide (CO 2 ), an abundant nontoxic, noncorrosive, and nonflammable greenhouse gas, is widely used as a stimulus trigger for existing gas-responsive materials. − Moreover, CO 2 , a vital molecule for life and environmental processes, has excellent biocompatibility and can readily penetrate into intracellular environments to aid in the stabilization of homeostasis and cellular pH levels and thus promote appropriate cell growth and cycle progression. , CO 2 -responsive materials and their derivatives are created by incorporating CO 2 -sensitive functional groups, such as amines, amidines, guanidines, imidazoles, and carboxylic acid groups, into the structure of various compounds. In aqueous solution, these functional groups react quickly with CO 2 to form carbamate-ammonium groups, which improves water solubility. − Imidazole has the highest p K a value, and thus a stronger basic strength, than other functional groups, and can thereby promote the formation of highly stable imidazole ring–CO 2 complexes within the structure of a material . For instance, Yu and co-workers reported that imidazole-containing polyphenylsulfone membranes showed excellent selective CO 2 separation performance owing to the strong interaction between CO 2 and the imidazole groups within the membranes .…”