Sulfated polysaccharides from Laminaria angustata: Structural features and in vitro antiviral activities

Saha, Sudipta; Navid, Mojdeh Heidary; Bandyopadhyay, Shruti S.; Schnitzler, Paul; Ray, Bimalendu

doi:10.1016/j.carbpol.2011.07.026

Cited by 69 publications

(51 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Compared with BCG-PSAW, two new characteristic absorption bands at 1241.93 cm −1 and 811.83 cm −1 were observed in the FT-IR spectra of sulfated derivatives (Fig. 3b), which were attributed to S O and C O S stretching vibration, respectively, according to previous works (Saha & Navid, 2012;). It suggested that BCG-PSAW was sulfated successfully.…”

Section: Preparation and Physicochemical Properties Of Bcg-psaw Sulfamentioning

confidence: 64%

Purification and characterization of a glucan from Bacillus Calmette Guerin and the antitumor activity of its sulfated derivative

Shao

et al. 2015

Carbohydrate Polymers

View full text Add to dashboard Cite

Section: Preparation and Physicochemical Properties Of Bcg-psaw Sulfamentioning

confidence: 64%

Purification and characterization of a glucan from Bacillus Calmette Guerin and the antitumor activity of its sulfated derivative

Shao

et al. 2015

Carbohydrate Polymers

View full text Add to dashboard Cite

“…Polysaccharides (sulfated polysaccharides in particular), poliketides, terpenoids or peptides with anti-HSV activities have been isolated from these marine organisms [10,11,12,13]. Glycolipids represent a less studied class of antiviral secondary metabolites [14].…”

Section: Introductionmentioning

confidence: 99%

Antiviral Sulfoquinovosyldiacylglycerols (SQDGs) from the Brazilian Brown Seaweed Sargassum vulgare

et al. 2013

View full text Add to dashboard Cite

Total lipids from the Brazilian brown seaweed Sargassum vulgare were extracted with chloroform/methanol 2:1 and 1:2 (v/v) at room temperature. After performing Folch partition of the crude lipid extract, the lipids recovered from the Folch lower layer were fractionated on a silica gel column eluted with chloroform, acetone and methanol. The fraction eluted with methanol, presented a strong orcinol-positive band characteristic of the presence of sulfatides when examined by TLC. This fraction was then purified by two successive silica gel column chromatography giving rise to fractions F4I86 and F4II90 that exhibited strong activity against herpes simplex virus type 1 and 2. The chemical structures present in both fractions were elucidated by ESI-MS and 1H/13C NMR analysis HSQC fingerprints based on their tandem–MS behavior as sulfoquinovosildiacylglycerols (SQDGs). The main SQDG present in both fractions and responsible for the anti-herpes activity observed was identified as 1,2-di-O-palmitoyl-3-O-(6-sulfo-α-d-quinovopyranosyl)-glycerol.

show abstract

“…The polysaccharides could inhibit HSV attachment to cells and direct inactivated viral particles with polysaccharide of the brown alga (Saha et al . ). The filtrate of Chlorella sp.…”

Section: Introductionmentioning

confidence: 97%

Inhibitory effect of Spirogyra spp. algal extracts against herpes simplex virus type 1 and 2 infection

et al. 2018

View full text Add to dashboard Cite

show abstract

Sulfated polysaccharides from Laminaria angustata: Structural features and in vitro antiviral activities

Cited by 69 publications

References 50 publications

Purification and characterization of a glucan from Bacillus Calmette Guerin and the antitumor activity of its sulfated derivative

Purification and characterization of a glucan from Bacillus Calmette Guerin and the antitumor activity of its sulfated derivative

Antiviral Sulfoquinovosyldiacylglycerols (SQDGs) from the Brazilian Brown Seaweed Sargassum vulgare

Inhibitory effect of Spirogyra spp. algal extracts against herpes simplex virus type 1 and 2 infection

Contact Info

Product

Resources

About