Sudden infant death syndrome in child care settings in the Netherlands

Jonge, G. A. De; Lanting, C.I.; Brand, Ronald; Ruys, J.H.; Semmekrot, B.A.; Wouwe, J.P. van

doi:10.1136/adc.2003.029884

Cited by 21 publications

(15 citation statements)

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“…A further risk factor is found in child care settings [44, 45], with a significantly higher number of SIDS cases occurring in child care than would expected from the time spent there. There are no clear explanations why child care settings are a risk factor for SIDS.…”

Section: Sudden Infant Death Syndromementioning

confidence: 99%

Cardiac Ion Channelopathies and the Sudden Infant Death Syndrome

Wilders

2012

ISRN Cardiology

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The sudden infant death syndrome (SIDS) causes the sudden death of an apparently healthy infant, which remains unexplained despite a thorough investigation, including the performance of a complete autopsy. The triple risk model for the pathogenesis of SIDS points to the coincidence of a vulnerable infant, a critical developmental period, and an exogenous stressor. Primary electrical diseases of the heart, which may cause lethal arrhythmias as a result of dysfunctioning cardiac ion channels (“cardiac ion channelopathies”) and are not detectable during a standard postmortem examination, may create the vulnerable infant and thus contribute to SIDS. Evidence comes from clinical correlations between the long QT syndrome and SIDS as well as genetic analyses in cohorts of SIDS victims (“molecular autopsy”), which have revealed a large number of mutations in ion channel-related genes linked to inheritable arrhythmogenic syndromes, in particular the long QT syndrome, the short QT syndrome, the Brugada syndrome, and catecholaminergic polymorphic ventricular tachycardia. Combining data from population-based cohort studies, it can be concluded that at least one out of five SIDS victims carries a mutation in a cardiac ion channel-related gene and that the majority of these mutations are of a known malignant phenotype.

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Section: Sudden Infant Death Syndromementioning

confidence: 99%

Cardiac Ion Channelopathies and the Sudden Infant Death Syndrome

Wilders

2012

ISRN Cardiology

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“…S›rt üstü yat›rma kampanyas› ile birlikte, Amerika Birleflik Devletlerinde (ABD), ABÖS'nun 1990-1994 y›llar› aras›ndaki insidans›n›n, 1983-1989 y›llar› aras›ndaki insidansa göre daha düflük oldu¤u, 1994 y›l›na göre 1995 y›l›nda %18,3 lük bir azalma oldu¤u saptanm›flt›r (2). Di¤er ülkelerdeki çal›flmalar da s›rt üstü yatma pozisyonunu önermektedir (26)(27)(28). Baz› çal›flmalar emzik kullan›m›n›n insidans› azaltt›¤›-n›, riski %90 oran›nda düflürdü¤ünü bildirmifltir (9,29).…”

Section: Ep‹dem‹yoloj‹unclassified

“…Sadece prenatal sigara kullan›m›n›n azalt›lmas›, riski teorik olarak %30 azaltabilir (17,30). Annenin hamilelikte ve/veya do¤um sonras› sigara kullan›m› yan› s›ra baban›n sigara içmesinin de pasif içicilik nedeni ile bebe¤i etkileyebilece¤i vurgulanm›flt›r (26,30). Ölüm sonras› incelemelerde perikardiyal nikotin metabolit oranlar› ABÖS olgular›nda, di¤er ölüm olgular›na oranla daha yüksek bulunmufltur (34,37).…”

Section: R‹sk Faktörler‹unclassified

“…Madde kullan›m›: Hamilelik döneminde madde ba¤›ml›s› annelerin bebekleri kontrol grubuna k›yasla daha yüksek düzeyde ABÖS'e maruz kalmaktad›r (26,34,(37)(38)(39). Annenin hamileli¤i süresince alkol kullan›m›n›n bebe¤in do¤um kilosunu düflürdü¤ü ve risk faktörü oluflturdu¤u bildirilmektedir (34,40).…”

Section: R‹sk Faktörler‹unclassified

“…Olgularda; genellikle düflük sosyoekonomik çevrede yaflam›n sürdürüldü¤ü, s›k üst solunum yollar› enfeksiyonu veya gastrointestinal sistem rahats›zl›¤› yafland›¤›, yaflam›n son iki haftas›nda gastrointestinal bozukluk, halsizlik, hafif atefl ya da aktivitede azalma nedeniyle doktora baflvuruldu¤u kaydedilmifltir (5,11,20,26,27,29).…”

Section: R‹sk Faktörler‹unclassified

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Ani Bebek Ölümü Sendromu

2006

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Bir yafl›n alt›ndaki bebeklerin ani ve beklenmedik ölümlerin-de; t›bbi ve sosyal öykü, olay yeri incelemesi, yap›lan otopsi ve tetkiklere karfl›n ölüm sebebi aç›klanamayan ölümler ani bebek ölümü sendromu (ABÖS) olarak tan›mlanmaktad›r. Geliflmifl ülkelerde yenido¤an döneminden sonra çocukluk ça¤›nda mortalitenin önemli nedenlerinden biridir. Bebekler genellikle uyku esnas›nda ölü bulunur ve ölüme neden olacak herhangi bir bulgu yoktur. Bugüne kadar birçok çal›flma yap›lmas›na karfl›n sorumlu mekanizmalar ve fizyopatoloji henüz ayd›nlat›-lamam›fl, ancak riski art›ran birçok etken tan›mlanm›flt›r. Ça-l›flmada; ABÖS güncel literatür ›fl›¤›nda de¤erlendirilmifl, risk etkenleri gözden geçirilmifl, s›kl›¤›n›n azalt›lmas›na yönelik ön-lemler belirtilmifl, otopsinin yan› s›ra öykünün önemi de vurgulanm›flt›r.Anahtar kelimeler: Ani bebek ölümü sendromu, bebek, risk faktörleri, uyku, otopsi. SUMMARYSudden infant death syndrome (SIDS) is the sudden death of an infant under 1 year of age which remains unexplained after a thorough case investigation, including performance of a complete autopsy, examination of the death scene, and review of the clinical history. It is a major cause of postneonatal mortality in developed countries. Generally, the infant is found dead after having been put to sleep and displays no signs of having suffered. Despite many years of research, underlying pathophysiology and mechanism of SIDS still remained controversial but numerous risk factors have been defined. In this article; SIDS and possible risk factors are reviewed and the precautions to decrease the incidence of SIDS and important role of autopsy and history were emphasized.

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Sudden and Unexpected Deaths in Infants and Sudden Infant Death Syndrome

Bajanowski¹,

Vennemann²

2014

Handbook of Forensic Medicine

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Sudden infant death syndrome in child care settings in the Netherlands

Cited by 21 publications

References 6 publications

Cardiac Ion Channelopathies and the Sudden Infant Death Syndrome

Cardiac Ion Channelopathies and the Sudden Infant Death Syndrome

Ani Bebek Ölümü Sendromu

Sudden and Unexpected Deaths in Infants and Sudden Infant Death Syndrome

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