Successful preferential formation of a novel macromolecular assembly—Trilayered polymeric micelle—That can incorporate hydrophilic compounds: The optimization of factors affecting the micelle formation from amphiphilic block copolymers

Polymeric micelles: authoritative aspects for drug delivery

“…Trilayered polymeric micelles from PEG-b-PLA copolymer served as containers for hydrophilic compounds and were incorporated into hydrogels as cross-linking agents. Resulting hydrogel could be used for releasing hydrophilic compounds in a sustained manner owing to degradation of copolymer and collapse of the micelle [268,269].…”

Novel anionic fluorine-containing amphiphilic self-assembly polymer micelles for potential application in protein drug carrier

“…The chemical structure and molecular weight of the graft copolymers were characterized by FTIR, 1 H NMR, 19 F NMR and GPC.…”

“…Well-defined characterization for the copolymers was performed through FTIR, 1 H NMR, 19 F NMR, and GPC. The graft copolymers could self-assemble into core/shell structure micelles in aqueous solution.…”

A zeolite as a tool for successful refolding of PEGylated proteins and their reassembly with tertiary structures

“…For example, stealth liposomes—liposomal vesicles having poly(ethylene glycol) (PEG) on the surface—can encapsulate hydrophilic compounds in internal spaces and deliver them to affected areas . In addition, polyion complex hollow vesicles (PICsomes) formed by the electrostatic interaction of cationic and anionic block copolymers, polymeric micelles formed from amphipathic block copolymers, nanogels, and dendrimers have been used to encapsulate and deliver hydrophilic compounds. Recently, attention has focused on nanoparticles, assembled from proteins, as drug carriers .…”