Subncute cutaneous lupus erythematosus-like gyrate erythema and hypertrichosis lanuginosa acquisita associated with uterine adenocarcinoma

McKenna, K.F.; Hayes, D P; McMillan, John

doi:10.1111/j.1365-2133.1992.tb00468.x

Cited by 14 publications

(8 citation statements)

References 9 publications

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“…Both the malignant tumour and dermatosis should follow a parallel course. Since the 1980s, several paraneoplastic SCLE cases have been reported in relation to malignancy involving the lung, breast, uterus, liver and lymphoma . The first case of head and neck malignancy associated with paraneoplastic SCLE was a supraglottic laryngeal SCC, reported by Chaudhry et al .…”

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confidence: 99%

Subacute cutaneous lupus erythematosus: a paraneoplastic phenomenon in oropharyngeal squamous cell carcinoma

et al. 2014

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confidence: 99%

Subacute cutaneous lupus erythematosus: a paraneoplastic phenomenon in oropharyngeal squamous cell carcinoma

et al. 2014

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“…The earliest case described was in 1982, involving a 70‐year‐old male with diffuse gyrate erythema, histologically suggestive of ‘chronic lupus erythematosus’, associated with lung carcinoma 2 . Following that case, other authors have reported the association between SCLE and adenocarcinoma of the stomach, 3 breast adenocarcinoma (two cases), 4,5 uterine adenocarcinoma, 6 Hodgkin’s disease 7 and with lung carcinoma (four cases) 2,8,9 . Our case broadens the list of malignancies associated with the development of SCLE (Table 1).…”

Section: Discussionmentioning

confidence: 99%

“…The association of SCLE with internal malignancy has been recognized since the early 1980s 2 . Subacute cutaneous lupus erythematosus, to date, has been associated with malignancies involving stomach, 3 breast, 4,5 uterus, 6 Hodgkin’s disease 7 and lung 2,8,9 …”

Section: Introductionmentioning

confidence: 99%

CASE REPORT Subacute cutaneous lupus erythematosus associated with hepatocellular carcinoma

Shumack²,

Morris

2001

Aust J Dermatology

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A 63-year-old man with a 4-year history of metastatic hepatocellular carcinoma secondary to chronic hepatitis B developed a rash affecting his arms, legs, thorax and back. Both clinical and histological examination suggested a diagnosis of subacute cutaneous lupus erythematosus (SCLE). The association of SCLE and hepatocellular carcinoma has not previously been reported. The SCLE persisted without remission and was still present at his death from metastatic hepatocellular carcinoma 3 months later. We also review other reported cases of SCLE as paraneoplastic dermatoses and apply McLean's criteria for paraneoplastic dermatosis.

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“…In women, colorectal carcinoma is the most observed associated malignancy, followed by lung cancer and breast cancer. In men, lung cancer is the most frequently encountered malignancy, followed by colorectal carcinoma 4–56 . Hair growth may occur from 2·5 years before the tumour is identified up to 5 years after diagnosis.…”

Section: Hypertrichosis Lanuginosa Acquisita As Paraneoplastic Manifementioning

confidence: 99%

Paraneoplastic hypertrichosis lanuginosa acquisita: uncommon or overlooked?

Slee¹,

Waal²,

Leeuwen³

et al. 2007

Br J Dermatol

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Acquired hypertrichosis lanugo-type or hypertrichosis lanuginosa acquisita (HLA) is often associated with metabolic and endocrine disorders and use of certain drugs. The occurrence of HLA with malignancy was first noted in 1865, and it has since been described in 56 patients as a paraneoplastic syndrome both in women and in men. Sometimes HLA occurs concurrent with acanthosis nigricans, papillary hypertrophy of the tongue, and glossitis. The predominance of female cases is striking. Malignancy-associated HLA seems to occur especially in the age group 40-70 years. In women with HLA the most frequent malignancy is colorectal cancer, followed in order by lung cancer and breast cancer; in men lung cancer is the malignancy most frequently associated with HLA, followed by colorectal cancer. In 3 years we saw 10 patients with HLA, in whom the malignancy was usually metastasized. Only one patient had local disease; after removal of the primary tumour it took 2 years before the lanugo hair recurred. The aetiology of the syndrome is not clear: no specific hormonal or biochemical abnormalities have been identified as yet. The difference between hirsutism and lanugo-type hypertrichosis is discussed. It is stressed that the appearance of lanugo-type hypertrichosis in body areas previously perceived by patients as 'hairless' is highly indicative of internal malignancy.

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Subncute cutaneous lupus erythematosus-like gyrate erythema and hypertrichosis lanuginosa acquisita associated with uterine adenocarcinoma

Cited by 14 publications

References 9 publications

Subacute cutaneous lupus erythematosus: a paraneoplastic phenomenon in oropharyngeal squamous cell carcinoma

Subacute cutaneous lupus erythematosus: a paraneoplastic phenomenon in oropharyngeal squamous cell carcinoma

CASE REPORT Subacute cutaneous lupus erythematosus associated with hepatocellular carcinoma

Paraneoplastic hypertrichosis lanuginosa acquisita: uncommon or overlooked?

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