Subacute cutaneous lupus erythematosus: a paraneoplastic phenomenon in oropharyngeal squamous cell carcinoma

Three cases of subacute cutaneous lupus erythematosus associated with malignancy: a late paraneoplastic phenomenon

“…In accordance with the literature, all our cases had a diagnosis of SCLE preceding the cancer detection. Several internal tumours have been associated with SCLE, including lung, breast, gastrointestinal, head and neck cancers, cholangiocarcinoma, and one case of in situ disease . Our cases were associated with aggressive or late‐stage tumours, with two of the three patients dying within 2 years, mirroring those reported .…”

“…Subacute cutaneous lupus erythematosus (SCLE) is frequently idiopathic and in some cases triggered by medications, but malignancy-associated SCLE is rarer. A case associated with squamous cell carcinoma of the tongue 1 was recently published in Clinical and Experimental Dermatology.…”

“…doi: 10.1111/ced.14181 Extranodal natural killer/T-cell lymphoma, nasal type (ENKL), is a rare non-Hodgkin lymphoma that is strongly associated with latent infection of Epstein-Barr virus (EBV). 1 Recent studies have demonstrated that certain chemokine receptors are associated with the pathology and clinical behaviour of lymphoma cells. 2 We report a case of ENKL expressing CC chemokine receptor 3 (CCR3) and CXC chemokine receptor 3 (CXCR3).…”

Trigger factors of cutaneous lupus erythematosus: a review of current literature

“…168 This pioneer description was followed by other reports suggesting a connection between SCLE and a variety of solid and non-solid tumors. The most frequently described associations involved lung carcinoma 169-172 and breast adenocarcinoma, 173-175 but there are also single reports attributed to gastric adenocarcinoma, 176 esophageal squamous-cell carcinoma, 177 hepatocellular carcinoma, 178 cholangiocarcinoma, 179 uterine adenocarcinoma, 180 laryngeal squamous-cell carcinoma, 181 oropharyngeal squamous-cell carcinoma, 182 papillary thyroid carcinoma, 183 meningioma 184 and Hodgkin’s disease. 185 Latency defined as the time period between the onset of the dermatosis and the diagnosis of the associated neoplasm ranged from 3 to 48 months.…”

S2k‐Leitlinie zur Diagnostik und Therapie des kutanen Lupus erythematodes – Teil 2: Therapie, Risikofaktoren und spezielle Fragestellungen

“…In Einzelfällen wurde ein CLE als paraneoplastische Dermatose beschrieben (zum Beispiel Lungen-, Magen-, Leber-, Mamma-, Prostata-und Uterus-Karzinome sowie Hodgkin-Lymphome); es handelt sich fast immer um einen SCLE [153][154][155][156][157][158][159][160][161][162][163][164].…”