Subclinical left ventricular dysfunction in Behcet's disease assessed by two-dimensional speckle tracking echocardiography

Abstract

Longitudinal myocardial systolic function assessed by STE, which is a sensitive marker of subclinical ventricular dysfunction is impaired in BD. Increased NT-proBNP levels may be a sign of subclinical ventricular dysfunction in these patients.

The role of two dimensional speckle -tracking echocardiography in a patient with Behçet's disease

“…Yağmur et al (8) have proven that left ventricular longitudinal systolic strain is significantly impaired and NT-proBNP is increased in correlation with mean left ventricular longitudinal strain in patients with BD compared with the healthy controls.…”

Cardiac pathology and modern therapeutic approach in Behçet disease

“…It was recognized that cardiac and arterial complications occur and are an important part in the complications of BD [1,4,7,[14][15][16]. Cardiac involvement in BD is frequent but is usually mild and asymptomatic.…”

“…In referred patients electrocardiography, echocardiography and, when used, computed tomography or magnetic resonance imaging analysis detect subtle cardiac changes in about one third of cases (they are listed in Table 1). It is, therefore, assumed that minor cardiac complications occur in around a third of patients with BD [1,[14][15][16][17]. As in other systemic complications, which are part of the diagnostic criteria, the cardiac pathology of BD is not specific.…”

“…In the literature the frequency of cardio-Behçet varies between 7% and 46% and this large difference shows that the real prevalence is unknown. Several reasons contribute to different statistics: a) definitions used for cardio-Behçet are not standardized; b) important national differences, and in countries with endemic experienced physicians detect cardiac complications more often than physicians where BD is rare; c) cardio-Behçet is really more frequent in some ethnicities [1,4,14,23]; and 4) referring habits, because if patients are sent to hospitals there are mandatory statistics, but if they are sent to private cardiologists the cases are rarely found in official statistics. Our group has a long experience with a small number of patients, mostly with migrant origins [1] and centers with many cases [18,22,23] have seen cardio-Behçet in < 10% of referred patients with BD.…”

Dilated Cardiomyopathy in Behcet′s Disease in a Young Male Patient

“…Degenerative changes and lysis of myocytes with cytoplasmic vacuolization, interstitial focal fibrinoid deposition, and fibroblast proliferation could be seen in CM due to BD [7,8]. Although sub-endocardial longitudinal fibers will be the first affected region in patients with BD, BD could effect any of the 3 layers of the heart or all of them at the same time [9]. Furthermore, CM in BD could be ischemic, non-ischemic, or inflammatory.…”