Study on the influence of cranberry extract Żuravit S·O·S® on the properties of uropathogenic Escherichia coli strains, their ability to form biofilm and its antioxidant properties

Wojnicz, Dorota; Sycz, Zuzanna; Walkowski, Stefan; Gabrielska, Janina; Włoch, Aleksandra; Alicja, Kucharska; Sokół‐Łętowska, Anna; Hendrich, Andrzej B.

doi:10.1016/j.phymed.2011.12.013

Cited by 25 publications

(20 citation statements)

References 52 publications

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“…Our results about the high antioxidant activity of berries (Table 3) are in line with Elberry et al [11], showing a high antioxidant activity of cranberry extract. Pronounced antioxidant and radical scavenging properties of cranberry was shown by Wojnicz et al [12]. Ethanol-soluble acidic components were used in order to determine the bioactivity of natural novel sources against oxidation [44].…”

Section: Resultsmentioning

confidence: 99%

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In Vitro Studies on the Relationship Between the Antioxidant Activities of Some Berry Extracts and Their Binding Properties to Serum Albumin

Namieśnik

Vearasilp

Nemirovski

et al. 2014

Appl Biochem Biotechnol

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The aim of this study was to investigate the possibility to use the bioactive components from cape gooseberry (Physalis peruviana), blueberry (Vaccinium corymbosum), and cranberry (Vaccinium macrocarpon) extracts as a novel source against oxidation in food supplementation. The quantitative analysis of bioactive compounds (polyphenols, flavonoids, flavanols, carotenoids, and chlorophyll) was based on radical scavenging spectrophometric assays and mass spectrometry. The total phenolic content was the highest (P < 0.05) in water extract of blueberries (46.6 ± 4.2 mg GAE/g DW). The highest antioxidant activities by 2,2-diphenyl-1-picrylhydrazyl radical scavenging assay and Cupric reducing antioxidant capacity were in water extracts of blueberries, showing 108.1 ± 7.2 and 131.1 ± 9.6 μMTE/g DW with correlation coefficients of 0.9918 and 0.9925, and by β-carotene linoleate assay at 80.1 ± 6.6 % with correlation coefficient of 0.9909, respectively. The water extracts of berries exhibited high binding properties with human serum albumin in comparison with quercetin. In conclusion, the bioactive compounds from a relatively new source of gooseberries in comparison with blueberries and cranberries have the potential as food supplementation for human health. The antioxidant and binding activities of berries depend on their bioactive compounds.

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Section: Resultsmentioning

confidence: 99%

“…Cranberry was investigated as a chemotherapeutic agent [11]. For this reason, presumably, they are used in folk medicine [12]. Physalis peruviana (PP) is a widely used medicinal herb for treating cancer, malaria, asthma, hepatitis, dermatitis, and rheumatism [13–16].…”

Section: Introductionmentioning

confidence: 99%

In Vitro Studies on the Relationship Between the Antioxidant Activities of Some Berry Extracts and Their Binding Properties to Serum Albumin

Namieśnik

Vearasilp

Nemirovski

et al. 2014

Appl Biochem Biotechnol

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“…The cell adhesion assay was performed essentially as described previously (Wojnicz et al 2012). Human uroepithelial cells from fresh urine of nonbacteriuric females were resuspended in PBS to give 10 5 cells per milliliter (Bürker chamber count).…”

Section: Methodsmentioning

confidence: 99%

Effect of asiatic and ursolic acids on morphology, hydrophobicity, and adhesion of UPECs to uroepithelial cells

2012

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Adhesion of bacteria to epithelial tissue is an essential step in the progression of the urinary tract infections. Reduction of virulence factors responsible for microbial attachment may help to decrease or inhibit colonization of the host organism by pathogens. In the age of increasing bacterial antibiotic resistance, more and more attention is being paid to the use of plants and/or their bioactive components in the prevention and treatment of human infections. Asiatic acid (AA) and ursolic acid (UA), two plant secondary metabolites, were used as potential antibacterial agents. The current study aimed to determine the possible impact of AA and UA on morphology, hydrophobicity, and adhesion of clinical uropathogenic Escherichia coli strains (UPEC) to the uroepithelial cells. Our work describes for the first time the effects exerted by AA and UA on virulence factors of UPECs. The impact of both acids on the cell surface hydrophobicity of the investigated strains was very weak. The results clearly show the influence of AA and UA on the presence of P fimbriae and curli fibers, morphology of the UPECs cells and their adhesion to epithelium; however, some differences between activities of AA and UA were found.

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“…Some of those plant natural products are essential in prevention and treatment of UTIs. The most commonly known in this field are cranberry products; however, antibacterial properties of many other plants are also well known [4]. In the present study, we focused on leaf extracts of plants used traditionally in prevention of UTIs.…”

Section: Introductionmentioning

confidence: 99%

Medicinal plants extracts affect virulence factors expression and biofilm formation by the uropathogenic Escherichia coli

et al. 2012

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Medicinal plants are an important source for the therapeutic remedies of various diseases including urinary tract infections. This prompted us to perform research in this area. We decided to focus on medicinal plants species used in urinary tract infections prevention. The aim of our study was to determine the influence of Betulapendula, Equisetum arvense, Herniaria glabra, Galium odoratum, Urtica dioica, and Vaccinium vitis-idaea extracts on bacterial survival and virulence factors involved in tissue colonization and biofilm formation of the uropathogenic Escherichia coli rods. Qualitative and quantitative analysis of plant extracts were performed. Antimicrobial assay relied on the estimation of the colony forming unit number. Hydrophobicity of cells was established by salt aggregation test. Using motility agar, the ability of bacteria to move was examined. The erythrocyte hemagglutination test was used for fimbriae P screening. Curli expression was determined using YESCA agar supplemented with congo red. Quantification of biofilm formation was carried out using a microtiter plate assay and a spectrophotometric method. The results of the study indicate significant differences between investigated extracts in their antimicrobial activities. The extracts of H. glabra and V. vitis-idaea showed the highest growth-inhibitory effects (p < 0.05). Surface hydrophobicity of autoaggregating E. coli strain changed after exposure to all plant extracts, except V. vitis-idaea (p > 0.05). The B. pendula and U. dioica extracts significantly reduced the motility of the E. coli rods (p < 0.05). All the extracts exhibited the anti-biofilm activity.

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Study on the influence of cranberry extract Żuravit S·O·S® on the properties of uropathogenic Escherichia coli strains, their ability to form biofilm and its antioxidant properties

Cited by 25 publications

References 52 publications

In Vitro Studies on the Relationship Between the Antioxidant Activities of Some Berry Extracts and Their Binding Properties to Serum Albumin

In Vitro Studies on the Relationship Between the Antioxidant Activities of Some Berry Extracts and Their Binding Properties to Serum Albumin

Effect of asiatic and ursolic acids on morphology, hydrophobicity, and adhesion of UPECs to uroepithelial cells

Medicinal plants extracts affect virulence factors expression and biofilm formation by the uropathogenic Escherichia coli

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