“…Particulate matter (PM) is the largest environmental cause of mortality around the globe, with fine particulate matterparticles with a diameter less than 2.5 μmestimated to cause millions of premature deaths annually. , Although PM is produced by a vast array of sources, most of the dominant contributors, especially in regions that do not depend on biomass for cooking and heating, tend to be outdoors (e.g., transportation, electric power generation, industry, forest fires, dust). While the built environment provides shelter from the elements, it is an incomplete filter; PM can penetrate buildings through open doors and windows, and localized studies have shown that smaller particles can enter through the small cracks and porous materials that comprise the outer shells of nearly all structures. , Given that Americans spend approximately 85–90% of their time indoors, with the vast majority in a private residence, , any effort to understand and limit damages from PM will fundamentally hinge on the degree to which outdoor air pollution penetrates indoors.…”