Studies on Performance Analysis and Computer Aided Design of Inverse Fluidized Bed Bioreactors with Nanosupport Particles

Narayanan, C. M.; Monangi, Tejaswi; Prasad, Harshika; Chakraborty, Neelanjana

doi:10.1515/ijcre-2014-0027

Cited by 7 publications

(3 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, traditional FBRs still have problems, such as catalyst settling, because nano-carriers are easily carried away in the reaction mixture, even at very low flow rates. This problem can be solved by applying circulating fluidized-bed bioreactors, as previously reported [131]. However, separation devices in FBRs are still necessary to recover the nano-catalysts, and the cost of nano-filtration remains high.…”

Section: Operation Modementioning

confidence: 99%

Magnetic Iron Oxide Nanomaterials for Lipase Immobilization: Promising Industrial Catalysts for Biodiesel Production

Hajareh Haghighi,

Binaymotlagh,

Palocci

et al. 2024

Catalysts

View full text Add to dashboard Cite

Biodiesel is a mixture of fatty acid alkyl esters (FAAEs) mainly produced via transesterification reactions among triglycerides and short-chain alcohols catalyzed by chemical catalysts (e.g., KOH, NaOH). Lipase-assisted enzymatic transesterification has been proposed to overcome the drawbacks of chemical synthesis, such as high energy consumption, expensive separation of the catalyst from the reaction mixture and production of large amounts of wastewater during product separation and purification. However, one of the main drawbacks of this process is the enzyme cost. In recent years, nano-immobilized lipases have received extensive attention in the design of robust industrial biocatalysts for biodiesel production. To improve lipase catalytic efficiency, magnetic nanoparticles (MNPs) have attracted growing interest as versatile lipase carriers, owing to their unique properties, such as high surface-to-volume ratio and high enzyme loading capacity, low cost and inertness against chemical and microbial degradation, biocompatibility and eco-friendliness, standard synthetic methods for large-scale production and, most importantly, magnetic properties, which provide the possibility for the immobilized lipase to be easily separated at the end of the process by applying an external magnetic field. For the preparation of such effective magnetic nano-supports, various surface functionalization approaches have been developed to immobilize a broad range of industrially important lipases. Immobilization generally improves lipase chemical-thermal stability in a wide pH and temperature range and may also modify its catalytic performance. Additionally, different lipases can be co-immobilized onto the same nano-carrier, which is a highly effective strategy to enhance biodiesel yield, specifically for those feedstocks containing heterogeneous free fatty acids (FFAs). This review will present an update on the use of magnetic iron oxide nanostructures (MNPs) for lipase immobilization to catalyze transesterification reactions for biodiesel production. The following aspects will be covered: (1) common organic modifiers for magnetic nanoparticle support and (2) recent studies on modified MNPs-lipase catalysts for biodiesel production. Aspects concerning immobilization procedures and surface functionalization of the nano-supports will be highlighted. Additionally, the main features that characterize these nano-biocatalysts, such as enzymatic activity, reusability, resistance to heat and pH, will be discussed. Perspectives and key considerations for optimizing biodiesel production in terms of sustainability are also provided for future studies.

show abstract

Section: Operation Modementioning

confidence: 99%

Magnetic Iron Oxide Nanomaterials for Lipase Immobilization: Promising Industrial Catalysts for Biodiesel Production

Hajareh Haghighi,

Binaymotlagh,

Palocci

et al. 2024

Catalysts

View full text Add to dashboard Cite

show abstract

“…Conventional packed bed and fluidized bed (including semi-fluidized bed) bioreactors are ruled out. The only choice is an inverse fluidised bed (of modified design) or a circulating fluidised bed 14, 15 . In the present study, we have considered biodiesel synthesis from neem oil and methyl acetate in inverse fluidised bed reactor that employs lipase immobilised nanosilica particles..…”

Section: Introductionmentioning

confidence: 99%

Studies on Biodiesel Synthesis Using Nanosilica Immobilised Lipase in Inverse Fluidized Bed Bioreactors

Narayanan

Pandey²

2018

JAC

Self Cite

View full text Add to dashboard Cite

I S S N 2 3 2 1 -807X V o l u m e 15 N u m b e r 1 J o u r n a l o f A d v a n c e s i n C h e m i s t r y 6072 | P a g e F e b r u a r y 2 0 1 8 h t t p s : / / c i r w o r l d . ABSTRACTBiodiesel synthesis from neem oil and methyl acetate using lipase catalyst immobilised in nanosilica particles in a continuous inverse fluidised bed bioreactor of modified design has been analysed. The process has been simulated mathematically by developing a multiparameter software package and subsequently verified through pilot plant tests(experiments).The improved performance characteristics of the bioreactor of proposed design have been highlighted. Graphical data have been presented to illustrate the dependence of reactor performance on system/operating parameters such as substrate flow rate, catalyst loading and molar ratio of oil to acetate in the blend(substrate solution).The downflow mode of operation is an added advantage of these bioreactors which tends to reduce their operating cost. Due to the use of nanoparticles, the effectiveness factor is close to unity and consequently, the global rate of transesterification is more or less equal to the intrinsic rate. This enhances the performance efficiency of the bioreactor.

show abstract

“…As stated earlier, reported studies on design and analysis of inverse fluidised bed bioreactors are scarce in literature. Performance characteristics of immobilized enzyme inverse fluidized bed bioreactors of modified design that employ nanosilica particles as support media have been analysed by Narayanan [4] et al The superior performance features of such reactors have been effectively highlighted by these authors.…”

Section: Introductionmentioning

confidence: 99%

Computer Aided Design and Performance Analysis of Inverse Fluidized Bed Biofilm Reactors with Special Reference to Bioplastic Synthesis

Narayanan¹,

Das²

2016

ACES

Self Cite

View full text Add to dashboard Cite

Poly Laevo Lactic Acid (PLLA), in spite of being an excellent bioplastic, has exorbitantly high market price due to the high cost of raw material (lactose, glucose, sucrose). Hence, its manufacture is being attempted starting from waste effluents such as cheese whey and molasses. Earlier studies on the same in fluidized bed and semifluidized bed biofilm reactors yielded encouraging results. The present study therefore involves design and analysis of inverse fluidized bed biofilm reactors for lactic acid synthesis. The performance features of the bioreactor have been studied both mathematically as well as experimentally. The inverse fluidized bed biofilm reactor has been found to provide more than 75% conversion of sucrose/lactose even at high capacities (high feed flow rates) exceeding 56,000 L/hr, within a reasonably low reactor volume. The fractional substrate conversion increases, though sluggishly, with increase in feed flow rate due to bed expansion and also with increase in cell mass concentration in biofilm due to enhancement in intrinsic rate of bioconversion. The inverse fluidized bed biofilm reactor of proposed design could be safely recommended for the commercial synthesis of polymer grade lactic acid from waste effluents such as cheese whey and molasses. The low operating cost of the bioreactor (due to downflow mode of operation) enhances the economy of the process. This would also help in significantly lowering the market price of the green plastic (PLLA) and shall promote its large scale manufacture and utilisation.

show abstract

Studies on Performance Analysis and Computer Aided Design of Inverse Fluidized Bed Bioreactors with Nanosupport Particles

Cited by 7 publications

References 16 publications

Magnetic Iron Oxide Nanomaterials for Lipase Immobilization: Promising Industrial Catalysts for Biodiesel Production

Magnetic Iron Oxide Nanomaterials for Lipase Immobilization: Promising Industrial Catalysts for Biodiesel Production

Studies on Biodiesel Synthesis Using Nanosilica Immobilised Lipase in Inverse Fluidized Bed Bioreactors

Computer Aided Design and Performance Analysis of Inverse Fluidized Bed Biofilm Reactors with Special Reference to Bioplastic Synthesis

Contact Info

Product

Resources

About