Studies on antivenom activity of Lactuca serriola methanolic extract against Buthus atlantis scorpion venom by in vivo methods

Bouimeja, Btissam; Yetongnon, K.H.; Touloun, Oulaid; Berrougui, Hicham; Laaradia, Mehdi Ait; Ouanaimi, Fouad; Chait, Abderrahman; Boumezzough, Ali

doi:10.1016/j.sajb.2019.07.044

Cited by 9 publications

(5 citation statements)

References 38 publications

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“…When animals were dosed with alcoholic extract of wild lettuce plant in conjunction with giving them the carcinogen, the effect on the level of AST transporter enzyme was less than if the carcinogen was given alone. The current results showed that the alcoholic extract of wild lettuce has a protective role for the liver against chemicals that may be the cause It is the ability of the alcoholic extract of the wild lettuce plant to maintain the cell membrane of hepatocytes and thus reduce the leakage of enzymes into the bloodstream and work to curb free radicals and reduce oxidative damage and this was confirmed by (Asif and others, 2020), and does not agree with (Bouimeja). et al, 2019), which demonstrated that the wild lettuce plant, when used as an anti-toxin, causes an increase in the levels of transporter enzymes.…”

Section: Aspartate Aminotransferase (Ast)mentioning

confidence: 57%

The protective effect of the alcoholic extract Lactuca serriola on some physiological parameters in the liver in white mice induced with Benzo(a)pyrene

Dawood¹,

Hameed²,

Sayer³

2022

Journal of Pharmaceutical Negative Results

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This study was conducted to investigate the possibility of using the alcoholic extract Lactuca serriole as a protective agent against the chemical compound benzopyrene that causes cancer. Alkanes are the dominant group in addition to the presence of phenol, alkene and ester, the highest concentration of the compound (1-Heneicosyl formate) (42.579) and the lowest concentration of the compound (1,6-Octadien3-ol, 3,7-dimethyl-, 2- aminobenzoate) by (1.009%), the results showed a significant decrease at the level of probability (P≥ 0.05) in the level of total protein in the liver in the group of animals that were dosed with carcinogenic benzopyrene in comparison with the healthy control group, while the effect on the level of total protein was less than in the group of animals that were dosed with carcinogenic benzopyrene, while the effect on the level of total protein was less than in the healthy control group In the groups that were dosed with alcoholic extract of wild lettuce plant with a concentration of 0.006mg/kg for the first group, 0.003 mg/kg for the second group, and a concentration of 0.0015mg/kg for the third group in conjunction with the benzene and pyrene carcinogen in comparison with the control group. It also showed a significant increase at the level of probability (0.05≥P) in the activity of the transaminase enzymes AST and ALT in the liver in the group of animals that were dosed with the carcinogenic substance benzopyrene compared to the healthy control group, while the effect on the level of enzymes was less in the groups that were dosed with alcoholic extract of wild lettuce plant with a concentration of 0.006mg/kg for the first group and 0.003mg/kg for the second group and 0.0015mg/kg for the third group in conjunction with the carcinogenic benzopyrene and compared with the control group.

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Section: Aspartate Aminotransferase (Ast)mentioning

confidence: 57%

The protective effect of the alcoholic extract Lactuca serriola on some physiological parameters in the liver in white mice induced with Benzo(a)pyrene

Dawood¹,

Hameed²,

Sayer³

2022

Journal of Pharmaceutical Negative Results

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“…Reducing power was assessed according to the method previously described [ 47 ]. 1 mL of various sample concentrations was added to 2.5 mL of phosphate buffer (200 mM, pH 6.6) and 2.5 mL of potassium ferricyanide (1%).…”

Section: Methodsmentioning

confidence: 99%

Antioxidant and Polyphenol-Rich Ethanolic Extract of Rubia tinctorum L. Prevents Urolithiasis in an Ethylene Glycol Experimental Model in Rats

et al. 2021

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Treatment of kidney stones is based on symptomatic medications which are associated with side effects such as gastrointestinal symptoms (e.g., nausea, vomiting) and hepatotoxicity. The search for effective plant extracts without the above side effects has demonstrated the involvement of antioxidants in the treatment of kidney stones. A local survey in Morocco has previously revealed the frequent use of Rubia tinctorum L. (RT) for the treatment of kidney stones. In this study, we first explored whether RT ethanolic (E-RT) and ethyl acetate (EA-RT) extracts of Rubia tinctorum L. could prevent the occurrence of urolithiasis in an experimental 0.75% ethylene glycol (EG) and 2% ammonium chloride (AC)-induced rat model. Secondly, we determined the potential antioxidant potency as well as the polyphenol composition of these extracts. An EG/AC regimen for 10 days induced the formation of bipyramid-shaped calcium oxalate crystals in the urine. Concomitantly, serum and urinary creatinine, urea, uric acid, phosphorus, calcium, sodium, potassium, and chloride were altered. The co-administration of both RT extracts prevented alterations in all these parameters. In the EG/AC-induced rat model, the antioxidants- and polyphenols-rich E-RT and EA-RT extracts significantly reduced the presence of calcium oxalate in the urine, and prevented serum and urinary biochemical alterations together with kidney tissue damage associated with urolithiasis. Moreover, we demonstrated that the beneficial preventive effects of E-RT co-administration were more pronounced than those obtained with EA-RT. The superiority of E-RT was associated with its more potent antioxidant effect, due to its high content in polyphenols.

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“…Общее распространение охватывает значительную территорию Европы и Азии, а также Северной Америки и Австралии, куда он был занесен (Lebeda et al, 2012;Красноборов и др., 1997Красноборов и др., , Chadha et al, 2019. Латук компасный является лекарственным растением (Janbaz et al, 2013;Bouimeja et al, 2019), а также дикорастущим родичем культурного салата-латука, проявившем резистентность к растительному патогену Bremia lactucae, являющемуся причиной заболевания мучнистой росой (Beharav et al, 2006). Поэтому изучение генетического разнообразия латука компасного, представленного многочисленными популяциями на всех континентах, является чрезвычайно важным (Van de Wiel, 2010).…”

Section: результатыunclassified

Distribution of the Prickly Lettuce Lactuca Serriola, the Siberian Lettuce Lactuca Sibirica and Blue Lettuce Lactuca Tatarica (Compositae) in Russia

Luneva¹,

Fedorova²

2020

PPN

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По материалам многочисленных научных публикаций, находящихся в открытом доступе, были усовершенствованы карты распространения трех видов сорных растений-латука компасного Lactuca serriola, латука сибирского Lactuca sibirica и латука татарского Lactuca tatarica (сем. Сложноцветные Compositae) на территории России. За основу были взяты карты из интерактивного ресурса «Агроэкологический атлас России и сопредельных стран: экономически значимые растения, их болезни, вредители и сорные растения», созданные двенадцать лет назад. Новые данные о распространении этих видов, а также появившиеся в последнее время в открытом доступе на вэб-ресурсах публикации прошлых лет, позволили выполнить ревизию сведений о зонах

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Studies on antivenom activity of Lactuca serriola methanolic extract against Buthus atlantis scorpion venom by in vivo methods

Cited by 9 publications

References 38 publications

The protective effect of the alcoholic extract Lactuca serriola on some physiological parameters in the liver in white mice induced with Benzo(a)pyrene

The protective effect of the alcoholic extract Lactuca serriola on some physiological parameters in the liver in white mice induced with Benzo(a)pyrene

Antioxidant and Polyphenol-Rich Ethanolic Extract of Rubia tinctorum L. Prevents Urolithiasis in an Ethylene Glycol Experimental Model in Rats

Distribution of the Prickly Lettuce Lactuca Serriola, the Siberian Lettuce Lactuca Sibirica and Blue Lettuce Lactuca Tatarica (Compositae) in Russia

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