Studies of a urinary biomarker of dietary inorganic sulphur in subjects on diets containing 1–38 mmol sulphur/day and of the half-life of ingested 34SO42−

Abstract

From a 24-h urine collection, IS intake from the habitual diet can be determined for groups of individuals. To predict individual intakes of IS, which may include high sporadic amounts from beer and wine, at least 48 h of urine collection would be required.

Small Intestinal Absorption of Methylsulfonylmethane (MSM) and Accumulation of the Sulfur Moiety in Selected Tissues of Mice

“…Studies of pharmacodynamics and tissue distribution of 35 S reveal a rapid decline of the 35 S after a single dose of MSM with the majority of the dose eliminated within 24 h and nearly 90% by 120 h, mainly via the urine [ 12 , 14 ], with more than 80% of the administered MSM having been metabolized before elimination in the urine [ 15 ]. The 8 h half-life of ingested inorganic sulfate is indicative of a similar rapid clearance [ 16 ] and is consistent with the regulation of a steady state pool of sulfate [ 17 ]. The present study provides novel findings for rapid carrier-independent, unsaturable intestinal absorption of MSM and how with chronic administration there is an increasing association of the sulfur moiety with proteins, which is consistent with how chronic feeding of MSM results in tissue retention [ 18 ].…”

The contribution of alliaceous and cruciferous vegetables to dietary sulphur intake

“…In other studies a moderately high total sulphur intake has been reported to be 38.2 mmol/day (high 42.2 mmol/day & very high 57.6 mmol/day) (Curno, Magee, Edmond, & Cummings, 2008). Using these figures a portion of the diet diaries in this study falls into the moderately high and high total sulphur intake category, however none of the diet diaries analysed could be classified as very high sulphur intake.…”

Dietary Factors in Sulfur Metabolism and Pathogenesis of Ulcerative Colitis

“…The sulfur content of food can be estimated using the sulfur-containing amino acids (methionine and cysteine) as surrogates, but this fails to account for sulfur-containing food modifiers or additives, such as sulfiting agents (e.g., potassium bisulfate, sodium bisulfate), sulfuric acid, or carrageenan [58]. Therefore, the most robust method of estimating dietary sulfur intake, including an estimate for inorganic sulfur, is through a 24–48 hour urine collection [59,60]. Because the primary dietary sources of sulfur are the sulfur-containing amino acids, in practice, quantification of sulfur-containing amino acid content has been used to create low- and high-sulfur diets [52,61].…”