2021
DOI: 10.34011/juriskesbdg.v13i1.1825
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Studi Literatur: Paparan Pestisida Dan Kejadian Gangguan Fungsi Ginjal Pada Petani

Abstract: Penyebab utama penyakit ginjal kronis (CKD) secara global adalah diabetes dan hipertensi, tetapi epidemi penyakit ginjal kronis yang tidak diketahui etiologi (CKDu) terjadi di Amerika Tengah dan Indonesia. Meskipun juga diamati pada wanita, CKDu terkonsentrasi pada pria di sektor pertanian. Oleh karena itu, kecurigaan awalnya jatuh pada paparan pestisida, tetapi stres panas kronis dan dehidrasi saat ini dianggap sebagai faktor etiologi utama. Menanggapi keprihatinan masyarakat dan ilmiah yang gigih tentang per… Show more

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“…The accumulation of pesticide exposure that enters the liver cannot be decomposed and excreted and stored in the liver which will disrupt the liver cells and organelles. The presence of damage to the liver parenchyma, and impaired permeability of the liver cell membrane so that enzymes free out of cells shown by the concentration of enzymes in the blood will increase (Dewi et al, 2021). Enzymes whose presence and levels in the blood are used as markers of impaired function include Serum Glutamic Oxsaloasetic Transamination (SGOT) and Serum Glutamic Pyruvic Transaminase (SGPT) (Tsani et al, 2017).…”
Section: Discussionmentioning
confidence: 99%
“…The accumulation of pesticide exposure that enters the liver cannot be decomposed and excreted and stored in the liver which will disrupt the liver cells and organelles. The presence of damage to the liver parenchyma, and impaired permeability of the liver cell membrane so that enzymes free out of cells shown by the concentration of enzymes in the blood will increase (Dewi et al, 2021). Enzymes whose presence and levels in the blood are used as markers of impaired function include Serum Glutamic Oxsaloasetic Transamination (SGOT) and Serum Glutamic Pyruvic Transaminase (SGPT) (Tsani et al, 2017).…”
Section: Discussionmentioning
confidence: 99%