Structure and properties of ultrathin poly-(3-hydroxybutirate) fibers modified by silicon and titanium dioxide particles

Abstract

The influence of small concentrations of nanoscale silicon and titanium dioxide particles on the structure, physicomechanical and sorption properties, thermal destruction resistance, and thermal and photo oxidant destruction of unwoven ultrathin fibrous materials that are prepared via electrostatic solution spin ning is studied. It is established that nanoscale particles favor the formation of thinner fibers with improved physical and mechanical parameters; good resistance to thermal, thermo and photo oxidant destruction; and positive dynamics of mesenchymal stem cells.

Composite tendon implant based on nanofibrillar polyhydroxybutyrate and polyamide filaments

“…The dependence of structure and properties of fibrous materials on the basis of PHB on technological parameters was described in previous articles . It was found that the smaller fiber diameter and the greater fiber packing density permitted more cells to be detected after inoculation and culture in the matrix.…”

Comparative Characterization of Melt Electrospun Fibers and Films Based on PLA‐PHB Blends: Diffusion, Drug Release, and Structural Features

“…In comparison to the fibrillar mats, the analogous drug release curves are presented but for the melt‐moulded bulk films. Both bio‐based polymer systems display two specific ranges such as nonlinear and linear ones, the physical meaning of which has been recently analyzed for the analogous solution‐electrospun ultrathin mats and the solution‐cast bulk films …”

Polymeric nanobiocomposites for biomedical applications

“…For instance, Liu et al 111 studied the mechanical properties of poly-lactic-coglycolic acid enriched with different types of ceramics as fillers. Similarly, utilizing the electrospinning method, Olkhov et al 166 compared the outcome of poly-(3-hydroxybutirate) nanobiocomposites using several nanofillers, which include silicon and titanium dioxide particles. It was found conclusive that the nanoparticles of titanium dioxide and silicon dioxide enhance the tensile strength and the modulus of polymeric matrix, whereas the nanosized hydroxyapatite improves the ductility and decreases the ability of water adsorption of the composites.…”

“…Similarly, PE and PLA have proven track records to be excellent candidates for bone tissue engineering due to their biocompatibility and non-toxicity, since they do not show much of an inflammatory response upon insertion into the body. 155,159,161 Some of the most accomplished fillers are silver, 162,163 carbon nanotube, 164 titanium dioxide, 95,165 silicon dioxide, 96,166 graphene dioxide, 158,167 and hydroxyapatite whiskers 128,168 and so forth These fillers can be successfully applied in dental and orthopedic application, since they can be easily incorporated into polymeric matrix by using methods, such as on-site precipitation, standard calandering technique or merely coating the nanofillers on to polymeric matrix. Among these fillers, carbon nanotubes have extensively been used for dental and orthopedic application owing to their superior ability to enhance mechanical properties, such as elastic modulus, young modulus, tensile strength upon addition of only minimal amount as less as 0.1% to the composites.…”

“…It was found conclusive that the nanoparticles of titanium dioxide and silicon dioxide enhance the tensile strength and the modulus of polymeric matrix, whereas the nanosized hydroxyapatite improves the ductility and decreases the ability of water adsorption of the composites. 111,154,166 Henceforth, studies have been focused on using two or more types of nanofillers or combinations of polymer matrix to attain optimum mechanical and biological features similar to that of the natural bone.…”