Structural Characteristics and Antioxidative Capability of the Soluble Polysaccharides Present in Dictyophora indusiata (Vent. Ex Pers.) Fish Phallaceae

Abstract

Dictyophora indusiata (Vent. ex Pers.) Fish Phallaceae (Chinese name Zhu-Sūn, the bamboo fungi) has been used as a medicinal mushroom to treat many inflammatory, gastric and neural diseases since 618 AD in China. We hypothesize that the soluble polysaccharides (SP) present in D. indusiata and their monosaccharide profiles can act as an important role affecting the antioxidative capability, which in turn would influence the biological activity involving anti-inflammatory, immune enhancing and anticancer. We obtained six SP fractions and designated them as D1, a galactoglucan; D2, a galactan; D3, the isoelectrically precipitated riboglucan from 2% NaOH; D4, a myoinositol; D5 and D6, the mannogalactans. The total SP accounted for 37.44% w/w, their molecular weight (MW) ranged within 801–4656 kDa. D3, having the smallest MW 801 kDa, exhibited the most potent scavenging effect against the α,α-diphenyl-β-picrylhydrazyl, •OH−, and •O2 − radicals, yielding IC50 values 0.11, 1.02 and 0.64 mg mL−1, respectively. Thus we have confirmed our hypothesis that the bioactivity of D. indusiata is related in majority, if not entirely, to its soluble polysaccharide type regarding the MW and monosaccharide profiles.

On the Basket Stinkhorn Mushroom Phallus merulinus (Phallaceae) in Mangalore, Karnataka, India

“…Hot water extract also showed broad spectrum antibacterial and antifungal principles (Oyetayo et al 2009). Phalus indusiatus is historically known to treat many inflammatory, gastric and neural disorders since 618AD in China (Ker et al 2011). As seen in P. indusiatus, alternatively a wide range of bioactive metabolites of medicinal and therapeutic potential are likely to exist in P. merulinus.…”

Mechanism of the immunostimulatory activity by a polysaccharide from Dictyophora indusiata

“…D. indusiata, an alkaline food in nature, contains various nutritious including protein, polysaccharide, mineral, vitamin, amino acids, thiamine, riboflavin, nicotinic acid and is good for the hypertensive, hypercholesterolemia and hyperlipidaemia. D. indusiata also has received considerable attention in biopharmaceutical fields because of the medicinal effect like mental tranquilization, antitumor, anticorrosive, enhance immunity, and so forth [1].…”

The Relationship between Liver Dysfunction and Arsenic Methylation in Mice

“…Our results illustrate that the lipid peroxidation reaction was induced by arsenic, after which it was taken in. The activity of SOD and GSH could reflect the ability of eradicating free radicals [30,31], and TAOC was the gross anti-oxidative element including macromolecular, micromolecular, and enzymes [32][33][34]. Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 …”