Structural and morphological changes in bacteria-membrane mimetic DPPE/DPPG/water systems induced by sulfadiazine

Oszlánczi, Ágnes; Bóta, Attila; Berényi, Szilvia; Klumpp, Erwin

doi:10.1016/j.colsurfb.2009.12.013

Cited by 7 publications

(1 citation statement)

References 26 publications

(28 reference statements)

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“…Additionally, from the biological point of view, we can consider the DPPC as a membrane model of mammalian cells and the DPPG as a bacterial membrane model. 21,22 Two different simulation series were performed to determine the structure, energetic and thermodynamics of the interaction between A n K polypeptides and the lipid membranes. At the rst series of simulations, the peptides were immersed in a periodic computational cell containing 128 lipids and about 6000 water molecules, totaling about 34 000 atoms.…”

Section: Simulation Detailsmentioning

confidence: 99%

Assessing the interaction between surfactant-like peptides and lipid membranes

et al. 2017

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Section: Simulation Detailsmentioning

confidence: 99%

Assessing the interaction between surfactant-like peptides and lipid membranes

et al. 2017

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Effects of ursolic acid on the structural and morphological behaviours of dipalmitoyl lecithin vesicles

Lőrincz¹,

Mihály²,

Németh³

et al. 2015

Biochimica et Biophysica Acta (BBA) - Biomembranes

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Effects of ursolic acid on the structural and morphological characteristics of dipalmitoyl lecithin(DPPC)-water system was studied by using differential scanning calorimetry (DSC), small- and wide-angle X-ray scattering (SWAXS), freeze-fracture method combined with transmission electron-microscopy (FF-TEM) and infrared spectroscopy (FT-IR). The surface of the uncorrelated lipid system is rippled or grained and a huge number of small, presumably unilamellar vesicles are present if the UA/DPPC molar ratio is 0.1 mol/mol or higher. Besides the destroyed layer packing of regular multilamellar vesicles, non-bilayer (e.g. cubic or hexagonal) local structures are evidenced by SAXS and FF-TEM methods. The ability of UA to induce non-bilayer structures in hydrated DPPC system originates from the actual geometry form of associated lipid and UA molecules as concluded from the FT-IR measurements and theoretical calculations. Beside numerous beneficial e.g. chemopreventive and chemotherapeutic effect of ursolic acid against cancer, their impact to modify the lipid bilayers can be utilized in liposomal formulations.

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Thermodynamic analysis and AFM study of the interaction of palmitic acid with DPPE in Langmuir monolayers

Sun

Hao

et al. 2014

Colloids and Surfaces A: Physicochemical and Engineering Aspect

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Structural and morphological changes in bacteria-membrane mimetic DPPE/DPPG/water systems induced by sulfadiazine

Cited by 7 publications

References 26 publications

Assessing the interaction between surfactant-like peptides and lipid membranes

Assessing the interaction between surfactant-like peptides and lipid membranes

Effects of ursolic acid on the structural and morphological behaviours of dipalmitoyl lecithin vesicles

Thermodynamic analysis and AFM study of the interaction of palmitic acid with DPPE in Langmuir monolayers

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