Striæ Gravidarum Their Relation to Adrenal Cortical Hyperfunction

To Study the Frequency and Pattern of Skin Changes in Pregnancy

“…One or more physiological changes of skin were observed in all the patients under study which is a general observation considering the skin types in the area of study [5] .Pigmentation of the skin was the commonest physiological change observed in 100% of Multipara and 90.6% primies. Similar high incidence of pigmentary change was observed in the study based at JIPMER [6] . Melasma was observed in only 30% of the patients under study.…”

“…Other Indian studies [5] showed lower incidence (8.8%) of melasma which was also observed in our study. Striae were most commonly observed on abdomen and more frequently in multipara than primies [6] . This is a common finding in all studies.…”

Risk factors associated with striae gravidarum

“…6 A 1959 study of 116 primigravid women in Australia followed throughout their pregnancies reported an SG rate of 60%. 7 This study also suggested possible associations between maternal obesity at baseline and weight gain in pregnancy.…”

A mechanochemical model of striae distensae

“…However, there is some debate about the relative importance of skin stretching in the aetiology of striae: one 16 group could not find any relationship between striae and the increase in abdominal girth among pregnant 17 females [11] and it has been noted that striae are rare over the extensor surfaces of joints (regions of skin 18 over a joint that is stretched when the joint is flexed) where the skin is subject to physiologic stretching 19 [12]. Less controversy exists regarding the possible role of glucocorticoids in the pathogenesis of striae.…”