Strain wave elastography for evaluation of renal parenchyma in chronic kidney disease

Menzilcioğlu, Mehmet Sait; Duymuş, Mahmut; Çitil, Serdal; Avcu, Serhat; Güngör, Gülay; Şahin, Tuna; Boysan, Serife Nur; Altunören, Orçun; Sarıca, Akif

doi:10.1259/bjr.20140714

Cited by 38 publications

(33 citation statements)

References 14 publications

(13 reference statements)

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“…The rest amount of related articles were 13 4,5,[8][9][10][11]13,14,25,[71][72][73][74] . But, pubmed search missed some articles 6,7,12,35,75 , that was mentioned in this paper (Table 1). the two adjacent tissue.…”

Section: Literature Reviewmentioning

confidence: 78%

Kidney Ultrasound Elastography: Review

Duymuş¹,

Menzilcioğlu²,

Gök³

et al. 2016

Kafkas J Med Sci

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Section: Literature Reviewmentioning

confidence: 78%

Kidney Ultrasound Elastography: Review

Duymuş¹,

Menzilcioğlu²,

Gök³

et al. 2016

Kafkas J Med Sci

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“…Of the few studies that examined the use of SWE to assess renal stiffness, and its relationship to native kidney function, four evaluated renal elasticity in CKD patients 8,38–40. Only two studies showed that SWE imaging, using ARFI-based technology, can be used to assess renal morphologic changes in patients with DKD 10,11.…”

Section: Discussionmentioning

confidence: 99%

Shear wave elastography imaging for assessing the chronic pathologic changes in advanced diabetic kidney disease

Hassan¹,

Loberant²,

Abbas³

et al. 2016

TCRM

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ObjectiveThe assessment of the grade of renal fibrosis in diabetic kidney disease (DKD) requires renal biopsy, which may be associated with certain risks. To assess the severity of chronic pathologic changes in DKD, we performed a quantitative analysis of renal parenchymal stiffness in advanced DKD, using shear wave elastography (SWE) imaging.Patients and methodsTwenty-nine diabetic patients with chronic kidney disease (CKD) grades 3–4 due to DKD, and 23 healthy subjects were enrolled. Combined conventional ultrasound and SWE imaging were performed on all participants. The length, width, and cortical thickness and stiffness were recorded for each kidney.ResultsCortical thickness was lower in patients with DKD than in healthy subjects (13.8±2.2 vs 14.8±1.6 mm; P=0.002) and in DKD patients with CKD grade 4 than in those with grade 3 (13.0±3.5 vs 14.7±2.1 mm; P<0.001). Cortical stiffness was greater in patients with DKD than in healthy subjects (23.72±14.33 vs 9.02±2.42 kPa; P<0.001), in DKD patients with CKD grade 4 than in those with grade 3 (30.4±16.2 vs 14.6±8.1 kPa; P<0.001), and in DKD patients with CKD grade 3b, than in those with CKD grade 3a (15.7±6.7 vs 11.0±4.2 kPa; P=0.03). Daily proteinuria was higher in DKD patients with CKD grade 4 than in those with grade 3 (5.52±0.96 vs 1.13±0.72; P=0.001), and in DKD patients with CKD grade 3b, than in those with CKD grade 3a (1.59±0.59 vs 0.77±0.48; P<0.001). Cortical stiffness was inversely correlated with the estimated glomerular filtration rate (r=−0.65, P<0.001) and with cortical thickness (r=−0.43, P<0.001) in patients with DKD.ConclusionsIn patients with advanced DKD, SWE imaging may be utilized as a simple and practical method for quantitative evaluation of the chronic morphological changes and for the differentiation between CKD grades.

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“…However, USE has not been reliable in differentiating between stages of CKD 101, 105 or grading fibrosis in transplanted kidneys 117. Also, the reported negative correlation between shear wave velocity and the progression of CKD is poorly understood.…”

Section: Clinical Applications Of Ultrasound Elastographymentioning

confidence: 99%

Ultrasound Elastography: Review of Techniques and Clinical Applications

et al. 2017

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Elastography-based imaging techniques have received substantial attention in recent years for non-invasive assessment of tissue mechanical properties. These techniques take advantage of changed soft tissue elasticity in various pathologies to yield qualitative and quantitative information that can be used for diagnostic purposes. Measurements are acquired in specialized imaging modes that can detect tissue stiffness in response to an applied mechanical force (compression or shear wave). Ultrasound-based methods are of particular interest due to its many inherent advantages, such as wide availability including at the bedside and relatively low cost. Several ultrasound elastography techniques using different excitation methods have been developed. In general, these can be classified into strain imaging methods that use internal or external compression stimuli, and shear wave imaging that use ultrasound-generated traveling shear wave stimuli. While ultrasound elastography has shown promising results for non-invasive assessment of liver fibrosis, new applications in breast, thyroid, prostate, kidney and lymph node imaging are emerging.Here, we review the basic principles, foundation physics, and limitations of ultrasound elastography and summarize its current clinical use and ongoing developments in various clinical applications.

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Strain wave elastography for evaluation of renal parenchyma in chronic kidney disease

Abstract: Determining a cut-off SI value between normal and diseased renal parenchyma can help in the diagnosis of CKD.

Cited by 38 publications

References 14 publications

Kidney Ultrasound Elastography: Review

Kidney Ultrasound Elastography: Review

Shear wave elastography imaging for assessing the chronic pathologic changes in advanced diabetic kidney disease

Ultrasound Elastography: Review of Techniques and Clinical Applications

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