Stoffwechselregulationen

Hoffmann, Auguste; Wertheimer, Ernst

doi:10.1007/bf01723722

Cited by 100 publications

(3 citation statements)

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“…(1942) IOO, 6I2. IT has been shown by Hoffmann & Wertheimer [1927] and by Wertheimer [1928] Schoenen, 1932;Wetzel & Held, 1936;Hausberger & Gujot, 1937;Hausberger & Neuenschwander, 1939] have confirmed and added to this finding. The experiments described in the present paper complete and extend the earlier investigations and deal more particularly with (1) the identification of the polysaccharide deposited in adipose tissue as glycogen, (2) the particular factors which induce the storage of glycogen in fatty tissue, and (3) the ultimate fate of adipose tissue glycogen ia -vivo.…”

supporting

confidence: 70%

“…The maximum values were attained on the average after 5 days; zero value was only attained after 2 weeks of recovery diet. The comparatively uniform liver and muscle glycogen values throughout the period of recovery feeding averaged 7-2 and 0*84 % [Wertheimer, 1926[Wertheimer, , 1927 that scission of suitable nervous connexions renders popliteal fat relatively immune to exploitation during phloridzin starvation. Hausberger [1935] was able to cut the nerve supply of the interscapular fat body of the mouse on one side only, and showed that an increase of glycogen and in its wake an accumulation of fat already became noticeable in the denervated half of the interscapular fat body 10 hr.…”

Section: Identification Of the Potysaccharide In Adipose Tissuementioning

confidence: 99%

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Glycogen and adipose tissue

Tuerkischer¹,

Wertheimer²

1942

The Journal of Physiology

148

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supporting

confidence: 70%

Section: Identification Of the Potysaccharide In Adipose Tissuementioning

confidence: 99%

Glycogen and adipose tissue

Tuerkischer¹,

Wertheimer²

1942

The Journal of Physiology

148

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“…The modern investigations of Schoenheimer and his associates (Schoenheimer, 1942) have demon- strated the state of continuous flux in which fat cells exist. A copious blood supply with potentialities scarcely inferior to those of some forms of muscle (Catchpole and Gersh, 1947), provides for a not inconsiderable oxygen consumption (Hoffmann and Wertheimer, 1927) ; indeed, there are varieties of fatty tissue, the so-called brown fat, with a respiration as great as that of the kidney (Fleischmann, 1929) and a rich complement of enzyme systems such as succinate and pyruvate oxidases, cytochrome oxidase, ascorbic acid and diphosphothiamine and lipases (Hook and Barron, 1941 ;Fawcett, 1947). Adipose tissue, therefore, should be looked upon as a highly specialised, well differentiated organ rather than a modification of connective tissue, although no doubt it shares some of the functions of the latter.…”

Section: Discussionmentioning

confidence: 99%

Growth and repair in adipose tissue

Cameron

Seneviratne

1947

J. Pathol.

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MUCH uncertainty exists about the growth and regeneration of adipose tissue. So far as we know, no-one has submitted the problem to a quantitative study, although all pathologists are aware that fat increases or decreases in amount under varying conditions of metabolism and a t various epochs of life. I n this paper we describe some experiments designed to show whether adult fatty tissue regenerates under the stimulus of partial removal of the parent mass. METHODSWe have worked with the bilateral folds of omentum-like tissue attached to the testes of rats. For convenience we refer to this as testicular omentum. Healthy male albino Wistar rats, 8 weeks old, were selected for uniformity in body weight. Under'open ether anssthesia and with strict aseptic precautions, the abdominal cavity was opened through a sub-umbilical mid-line incision and about half of one or both testicular omenta removed. Gentle traction on the testis was necessary for this manceuvre, but no permanent damage of that organ resulted in any of the animals. The stump of the omentum was ligatured with cotton thread ; in a few animals no ligature was used, bleeding being controlled with a cautery. The abdomen was closed with two layers of continuous cotton sutures. Little bleeding occurred and the animals made an uninterrupted recovery. Stitch abscesses developed in several animals but cleared up without much trouble after a few weeks. Four groups of rats were employed. I n one group, about half of the left testicular omentum, in the second, half of both left and right testicular omenta was removed. In the third, a portion of the gastric omentum was detached, the amount of tissue being about half of that obtained from the testicular omentum because the gastric omentum is a scanty structure in 8-weeks-old rats. This group served aa a control to the first and second groups, since all operative procedures were aimilar in the three categories, with the exception of the type of tissue removed. A fourth series, killed at the time of operation, provided data on the normal weights of the structures concerned. The table shows a striking similarity in body weights between all 4 groups, so that we feel justified in applying the mean values for the testicular omenta obtained from group 4 to the other groups in assessing repair of the omental adipose tissue.In addition, we removed testicular omentum from a further group of 8weeks-old rats for the purpose of studying the histological changes in the stump at varying times after resection. Finally, autologous grafting of the testicular J. PATE. BACT.-VOL. LIX 665

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The direct effect of insulin on organ cultures of brown fat

Sidman

1956

Anat. Rec.

141

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Stoffwechselregulationen

Cited by 100 publications

References 0 publications

Glycogen and adipose tissue

Glycogen and adipose tissue

Growth and repair in adipose tissue

The direct effect of insulin on organ cultures of brown fat

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