Stir bar sorptive extraction and thermal desorption–gas chromatography–mass spectrometry for the measurement of 4-nonylphenol and 4-tert-octylphenol in human biological samples

Stir bar sorptive extraction with in situ derivatization and thermal desorption-gas chromatography–mass spectrometry for measurement of phenolic xenoestrogens in human urine samples

“…In addition, an analytical method for the determination of endocrine disrupting chemicals (EDCs) has been reported [32,33]. We have reported the determination of OP and NP in tap and river water samples [34] and biological samples [35] by SBSE without derivatization. On the other hand, SBSE with in situ derivatization has been successfully used in the determination of phenolic compounds in various samples [36][37][38][39].…”

Analytical Methods for the Quantification of Bisphenol A, Alkylphenols, Phthalate Esters, and Perfluoronated Chemicals in Biological Samples

“…[54][55][56][57][58] Our group reported on the analysis of NP and OP in biological fluids, such as serum, plasma, and urine. [59][60][61][62][63][64] For example, SBSE was used in combination with thermal desorption (TD) GC/MS for the determination of NP and OP in human urine and plasma samples. 60 When five human urine samples and three human plasma samples from healthy volunteers were analyzed, NP and OP were not detected in any of the urine samples.…”

“…[59][60][61][62][63][64] For example, SBSE was used in combination with thermal desorption (TD) GC/MS for the determination of NP and OP in human urine and plasma samples. 60 When five human urine samples and three human plasma samples from healthy volunteers were analyzed, NP and OP were not detected in any of the urine samples. However, NP and OP were found at levels of 0.2 -0.3 ng/mL and 0.1 -0.2 ng/mL, respectively, in the human plasma samples.…”

Determination of p-tert-Octylphenol in Blood and Tissues by Gas Chromatography Coupled with Mass Spectrometry

“…OP is found in many consumer products, including detergents, vinyl paints, electrical insulating varnishes, pesticides, ink, paper, and tires (5). Trace amounts of OP have been found in human blood samples (6,7). OP has been measured in biological matrices using gas chromatography (GC) or high-performance liquid chromatography (HPLC) coupled with various detection techniques.…”

“…Kawaguchi et al (7) measured OP in human urine and plasma samples by stir bar sorptive extraction coupled with thermal desorption and GC-MS. Liu et al (9) developed an online LC method coupled with photodiode-array detection and MS with restricted access media pre-column and dilution line for the determination of OP in serum samples. Yang et al (10) analyzed OP in biological samples using direct immersion solid-phase microextraction and headspace on-fiber silylation coupled with GC-MS. Ye et al (11) measured OP in breast milk using isotope dilution online solid-phase extraction coupled with HPLC-MS-MS.…”