Stimation of reference interval of lipid profile in Assamese population

Das, Madhumita; Saikia, Mauchumi

doi:10.1007/s12291-009-0034-x

Cited by 18 publications

(27 citation statements)

References 3 publications

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“…Recent studies from different geographical locations of India have established reference intervals for certain biochemical parameters and also identified significant changes in liver markers and lipid levels in healthy Indian population [16][17][18][19][20][21]. Furthermore, we have documented that the renal and cell integration markers like creatinine, AST and GGT were lower in females than males as supported by previous studies done elsewhere [22,23].…”

Section: Discussionsupporting

confidence: 84%

Hematological and Biochemical Parameters in Apparently Healthy Indian Population: Defining Reference Intervals

Sairam¹,

Domalapalli

Maruthamuthu

et al. 2013

Ind J Clin Biochem

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Clinical reference intervals among Indian population are poorly defined. Therefore, there is an urgent need to establish local clinical laboratory reference intervals for healthy Indian population. The present study aimed to identify the 95 % reference interval for hematological and biochemical parameters in apparently healthy Indian population. We undertook a multicentric cross-sectional study conducted at Apollo Hospitals Educational and Research Foundation across India. Of which 10,665 reference individuals identified as healthy by physicians. The 95 % of the reference distribution was estimated using 2.5th and 97.5th percentile reference limits. The 95 % reference intervals for hemoglobin (Males: 12.3-17 g/dL; Females: 9.9-14.3 g/dL), platelet count (Males: 1.3-3.8; Females: 1.3-4.2 Lakhs/µL), erythrocyte sedimentation rate (Males: 2-22; Females: 4-55 mm/h), serum uric acid in males: 3.5-8.2 mg/dL, gamma glutamyl transferase (Males: 13-61 U/L), fasting blood glucose (Males: 78-110 mg/dL), total cholesterol (Males: 115-254 mg/dL), low density lipoprotein (Males: 60-176 mg/dL) and triglycerides (Males: 55-267 mg/dL, Females: 52-207 mg/dL) were different from currently used reference values. Additionally need for gender based partitioning were observed for triglycerides and gamma glutamyl transferase. The observed findings are of clinical significance and it needs to be validated with additional community based studies.

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Section: Discussionsupporting

confidence: 84%

Hematological and Biochemical Parameters in Apparently Healthy Indian Population: Defining Reference Intervals

Sairam¹,

Domalapalli

Maruthamuthu

et al. 2013

Ind J Clin Biochem

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“…According to the latest ATP III guideline the optimal level of TC, TG, HDL and LDL are < 200 mg/dl, < 150 mg/dl, > 40 mg/dl and < 100 mg/dl respectively 26 . Madhumita et al has shown from a study conducted on 1485 Assamese subjects that an average healthy urban Assamese population has a TC, TG, HDL and LDL value of 170 mg/dl, 110 mg/dl, 40 mg/dl and 103 mg/dl respectively 27 . Considering the ATP III criteria as well as the values provided by study of Madhumita et al, the hyperuricemic cases in the present study are associated with dyslipidemia.…”

Section: Discussionmentioning

confidence: 99%

A correlative study of uric acid with lipid profile

Sarmah

2013

Asian J Med Sci

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Objective: the study was conducted to verify the association of hyperuricemia with lipid profile in a group of Assamese people so as to take necessary precautions from developing future cardiovascular disease (CVD). Methods: lipid profile (total cholesterol, triglycerides, HDL and LDL) were estimated in sixty hyperuricemic Assamese people who had no previous history of CVD to ascertain the pattern of their association between uric acid and lipid profile if any. Results: The study proves a significant positive correlation (p < 0.005) between uric acid and TC, TG and LDL, and a significant negative correlation (p < 0.005) between uric acid and HDL. Conclusion: The study thus shows that hyperuricemia is associated with dyslipidemia which may predispose to future CVD. So treating such subject for hyperuricemia and dyslipidemia can very well reduce cardiovascular morbidity. DOI: http://dx.doi.org/10.3126/ajms.v4i2.7893 Asian Journal of Medical Sciences 4(2013) 8-14

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“…Available global data have clearly established the relationship of lipids and other risk factors with cardiovascular and cerebrovascular events [3][4][5][6][7][8][9][10][11]. It is therefore essential to establish a reference range of the values of serum lipids for a given population as only a few studies have been carried out in other regions of India [12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

To Establish the Reference Intervals of Lipid Profile in Punjab

et al. 2012

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Overnight fasting samples of 1,031 apparently healthy people of Punjab visiting the hospital over a period of 3 years were tested for serum lipid profile. The mean ± SD of serum total cholesterol, triglycerides, high density lipoprotein cholesterol, low density lipoprotein cholesterol and very low density lipoprotein cholesterol in mg/dl were 182.2 ± 33.9, 122.4 ± 33.4, 44.1 ± 6.8, 113.9 ± 32.0, 24.6 ± 7.1 respectively. When these subjects were grouped according to age and sex, no appreciable difference was observed between most of the groups. Serum triglycerides were found to be low and HDL-C was high in females when compared with males of similar age and vice versa. With advancing age, total cholesterol and low density lipoprotein cholesterol levels were found to be higher in women. The present study suggests that the obtained lipid values should be taken into consideration during clinical evaluation.

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Stimation of reference interval of lipid profile in Assamese population

Abstract: 170 (93-263); 110 (40-256); 40 (23-73); 103 (40-173) and 22 (8-51)

Cited by 18 publications

References 3 publications

Hematological and Biochemical Parameters in Apparently Healthy Indian Population: Defining Reference Intervals

Hematological and Biochemical Parameters in Apparently Healthy Indian Population: Defining Reference Intervals

A correlative study of uric acid with lipid profile

To Establish the Reference Intervals of Lipid Profile in Punjab

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