Sterilization of narrow tube inner surface using discharge plasma, ozone, and UV light irradiation

Kitazaki, Satoshi; Tanaka, Akimasa; Hayashi, Nobuya

doi:10.1016/j.vacuum.2014.06.014

Cited by 33 publications

(24 citation statements)

References 10 publications

(1 reference statement)

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“…[154] CAP can easily reach narrow, confined spaces and microgrooves on surfaces. [82] and mobility of plasma gas can allow for treatment of microspaces [123,155] . Recent studies reported CAP efficacy in reducing microbial contamination adhered to rough surfaces of chicken skin [151] , titanium implant surfaces [156] and root canals, especially in dry state conditions.…”

Section: Cap As a Potential Technique For Thin Tissue Sterilizationmentioning

confidence: 99%

Terminal sterilization: Conventional methods versus emerging cold atmospheric pressure plasma technology for non‐viable biological tissues

Marsit

Sidney

Branch

et al. 2016

Plasma Processes & Polymers

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Tissue products are susceptible to microbial contamination from different sources, which may cause disease transmission upon transplantation. Terminal sterilization using gamma radiation, electron‐beam, and ethylene oxide protocols are well‐established and accepted, however, such methods have known disadvantages associated with compromised tissue integrity, functionality, safety, complex logistics, availability, and cost. Non‐thermal (cold) atmospheric pressure plasma (CAP) is an emerging technology that has several biomedical applications including sterilization of tissues, and the potential to surpass current terminal sterilization techniques. This review discusses the limitations of conventional terminal sterilization technologies for biological materials, and highlights the benefits of utilizing CAP.

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Section: Cap As a Potential Technique For Thin Tissue Sterilizationmentioning

confidence: 99%

Terminal sterilization: Conventional methods versus emerging cold atmospheric pressure plasma technology for non‐viable biological tissues

Marsit

Sidney

Branch

et al. 2016

Plasma Processes & Polymers

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show abstract

“…Microfluidic cell culture poses elicitation of specific sterilization requirements. Current methods of sterilization for the removal of microorganisms from medical devices include steam autoclaving, ethylene oxide treatment, UV and hydrogen peroxide treatment [7][8][9]. However, the techniques have obvious drawbacks and cannot be applied for sterilization of some materials such as polymeric medical devices and heat-sensitive biomaterials [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

“…the surfaces can cause hemolysis and become carcinogen [7,10]. In addition, the sterilization period is very long [8]. Hydrogen peroxide is not toxic and it has a highly microbicidal effectiveness against a broad spectrum of microorganisms [15].…”

Section: Introductionmentioning

confidence: 99%

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Sterilization of PMMA microfluidic chips by various techniques and investigation of material characteristics

Yavuz

Oliaei

Çetin

et al. 2016

The Journal of Supercritical Fluids

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a b s t r a c tThe sterilization of microfluidic chips is a vital step of the fabrication process prior to the customer use in biomedical applications. The aim of this study was to analyze the influence of different sterilization techniques and to compare the characteristics of the material before and after sterilization of polymethylmethacrylate (PMMA) microchips. For this, supercritical carbon dioxide (SC-CO 2 ) along with standard sterilization methods such as ultraviolet (UV), heat (autoclaving), ethylene oxide (EtO) and hydrogen peroxide (H 2 O 2 ) were applied. The treated microchips were analyzed by Scanning Electron Microscopy, Differential Scanning Calorimetry, Fourier Transform Infrared Spectroscopy and Laser Scanning Microscopy in order to ascertain any changes in the chemical structure and surface morphology. The optimum sterilization parameters for SC-CO 2 were elicited as 120 bar, 40 • C and 60 min which provided complete sterility and did not alter the main properties of the polymer along with EtO and H 2 O 2 sterilizations unlike heat and UV treatments. However, surface roughness and microchannel profiles were negatively affected. Although complete sterility was achieved, each protocol has its own strengths and weaknesses.

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“…As the results of these advantages, plasma sterilization has attracted much attention in recent years. For example, Hayashi et al developed a high-speed method for sterilizing PET bottles using a microwave plasma torch [3][4][5]. Yagyu et al suggest that glow discharge plasma irradiation for some kinds of plants, such as Bean sprouts, increased their growth rate [6].…”

Section: Introductionmentioning

confidence: 99%

Optical Study of Laser Ablation Plasma Irradiation for the Bacteria Sterilization using Metal Oxide Target

Kawasaki

Ohshima

Yagyu

et al. 2016

Trans. Mat. Res. Soc. Japan

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PLA plasma sterilization of yeast fungus and spore-forming bacteria was performed using Ti and TiO2 target. The experimental results suggested that both the yeast fungus and spore-forming bacteria could be sterilized by plasma irradiation generated by pulsed laser ablation method. The effect using pure Ti target slightly stronger than that of the TiO2 target. This results suggests that the main sterilization factors were considered to be high energy metal atoms and/or ions in this system.

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Sterilization of narrow tube inner surface using discharge plasma, ozone, and UV light irradiation

Cited by 33 publications

References 10 publications

Terminal sterilization: Conventional methods versus emerging cold atmospheric pressure plasma technology for non‐viable biological tissues

Terminal sterilization: Conventional methods versus emerging cold atmospheric pressure plasma technology for non‐viable biological tissues

Sterilization of PMMA microfluidic chips by various techniques and investigation of material characteristics

Optical Study of Laser Ablation Plasma Irradiation for the Bacteria Sterilization using Metal Oxide Target

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