Status of carbohydrate and lipid metabolism in obese patients with type 2 diabetes mellitus after biliopancreatic diversion surgery

Ершова, Е. В.; Yashkov, Yuriy Ivanovich

doi:10.14341/2071-8713-3862

Cited by 8 publications

(17 citation statements)

References 19 publications

(25 reference statements)

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“…К преимуществам операции BPD, помимо стабиль-ного снижения веса и стойкого воздействия на липидный и углеводный обмены, относятся отсутствие выключе-ния желудка из пищеварения, отсутствие инородного тела в верхней части желудка, необходимости допол-нительных манипуляций, как например, регулировки бандажа [23,44]. Кроме того, при BPD-DS и модифи-кации SADI удается сохранить привратник, отсутствует постгастрэктомический синдром (демпинг-синдром), практически не возникают язвы анастомоза [45].…”

Section: шунтирование желудка с гастроеюноанастомозом по руunclassified

“…Диагностика, контроль, лечение Diagnosis, control, treatment на исходную тяжесть основного контингента больных, составляет от 0,1 до 1,2% [42,44,46,47]. Смертность в долгосрочном периоде (10,0±6,3 года наблюде-ния) составляет 6,1%, а совокупная смертность через 30 дней, 90 дней и 1 год составляет 0,2%, 0,3% и 0,5% соответственно [46].…”

Section: сахарный диабет Diabetes Mellitusunclassified

“…После операции у больных СД2 наблюдается полная ремиссия или значительное улучшение его тече-ния, а также значительное снижение смертности от свя-занных с СД2 причин [19]. Среди всех бариатрических операций БПШ обладает наиболее выраженным анти-диабетическим эффектом [23,44].…”

Section: влияние на течение сахарного диабетаunclassified

“…На про-тяжении пятилетнего срока наблюдения уровень HbA 1c был в норме. К концу периода наблюдения всем пациен-там была постепенно отменена инсулинотерапия и лишь 1,4% пациентов продолжали принимать пероральные сахароснижающие препараты (по сравнению с исход-ными 44%) [44].…”

Section: влияние на течение сахарного диабетаunclassified

“…Ершовой и Ю.И. Яшкова -98,6% [44]. Сле-дует отметить, что хирургическое вмешательство у па-циентов с коротким анамнезом СД2 дает более высокую частоту ремиссии по сравнению с пациентами с большей длительностью заболевания [68], что, вероятно, следует объяснить прогрессирующим апоптозом -клеток под-желудочной железы в процессе развития заболевания.…”

Section: влияние на течение сахарного диабетаunclassified

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Evolution of biliopancreatic diversion in the treatment of morbid obesity and type 2 diabetes mellitus

et al. 2017

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The prevalence of morbid obesity is on the rise. Surgical intervention for the treatment of morbid obesity has been shown to provide high metabolic efficiency, acquiring a special role in the treatment of type 2 diabetes mellitus. Various surgical procedures are used in treating morbid obesity. These include gastric-bypass surgery and biliopancreatic bypass diversion (BPD), each with various advantages of its own. In recent years, BPD (also referred to as the Scopinaro procedure) has evolved and been modified into the single anastomosis duodeno-ileal (SADI) procedure. Like other types of BPD, the SADI procedure effectively reduces excess body weight and promotes normalisation of carbohydrate and lipid metabolism, leading to a reduced frequency of insulin therapy and use of antidiabetic drugs. The potential benefits of the procedure include reduced operative time and a reduced incidence of internal hernias. Studies have also shown that the SADI procedure results in fewer early and late post-operative complications. Given the effectiveness of the procedure, it is necessary to increase the number and duration of observations made to enable further insight into the long-term efficacy and use of the SADI procedure.

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Section: шунтирование желудка с гастроеюноанастомозом по руunclassified

Section: сахарный диабет Diabetes Mellitusunclassified

Section: влияние на течение сахарного диабетаunclassified

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Evolution of biliopancreatic diversion in the treatment of morbid obesity and type 2 diabetes mellitus

et al. 2017

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SADI-S 250 vs Roux-en-Y Duodenal Switch (RY-DS): Results of 5-Year Observational Study

Yashkov¹,

Бордан²,

Torres

et al. 2020

OBES SURG

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Bariatric Surgery

et al. 2022

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Today, bariatric surgery is the most effective treatment of obesity. Restrictive surgeries are aimed at reducing the volume of the stomach. Such operations have the least adverse effects in terms of the physiology of digestion. However, they are less effective in losing weight. Mixed operations (gastric bypass surgery, biliopancreatic diversion) decrease the volume of the stomach and the length of the small intestine. Mixed operations tend to provide more pronounced results in a short time. However, by seriously disrupting the digestion and absorption of the food, they may result in severe micronutrient deficiencies. The assimilation of lipophilic substances is severely impaired as the biliopancreatic system is almost disconnected from the digestive tract. Furthermore, the assimilations of not only fats and essential fatty acids but also all fat-soluble vitamins are interrupted. In most cases, these patients need to take high-dose micronutrient supplements for their whole life. Usually, deficiencies of vitamins A, D, E, C, and vitamins of group B, especially B1, B6, B12, niacin, and folate, as well as iron, calcium, phosphate, magnesium, zinc, copper, and selenium, are found after operations. Restrictive operations, although less traumatic for the digestive system, significantly disrupt the digestion and absorption of nutrients, especially those in which the stomach plays a significant role in its digestion. These are proteins, folate, niacin, vitamin B12, iron, and copper. Bariatric surgical procedures are like a double-edged sword. They can be highly effective in the treatment of obesity and related complications; nevertheless, they are surgeries with serious potential for complications.

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Status of carbohydrate and lipid metabolism in obese patients with type 2 diabetes mellitus after biliopancreatic diversion surgery

Cited by 8 publications

References 19 publications

Evolution of biliopancreatic diversion in the treatment of morbid obesity and type 2 diabetes mellitus

Evolution of biliopancreatic diversion in the treatment of morbid obesity and type 2 diabetes mellitus

SADI-S 250 vs Roux-en-Y Duodenal Switch (RY-DS): Results of 5-Year Observational Study

Bariatric Surgery

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