SADI-S 250 vs Roux-en-Y Duodenal Switch (RY-DS): Results of 5-Year Observational Study

Yashkov, Yu I; Бордан, Н С; Torres, Antonio; Malykhina, Alexandra; Бекузаров, Д. К.

doi:10.1007/s11695-020-05031-z

Cited by 47 publications

(26 citation statements)

References 29 publications

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“…No RCT with 5-year follow-up was found comparing single-anastomosis duodenoileal bypass with sleeve gastrectomy (SADI-S) with other procedures in terms of T2DM remission. However, SADI-S has been proposed as an alternative to LDS for these outcomes due to its less dangerous side effect profile [33], so it would be interesting to compare not only LOAGB and LDS, but SADI-S as well.…”

Section: Discussionmentioning

confidence: 99%

Comparative Effectiveness of Bariatric Surgeries in Patients with Type 2 Diabetes Mellitus and BMI ≥ 25 kg/m2: a Systematic Review and Network Meta-Analysis

et al. 2021

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Purpose In patients with type 2 diabetes mellitus (T2DM), bariatric surgery appears to be more effective than medical treatment (MT) at improving glycaemic control and decreasing cardiovascular risk. However, long-term effectiveness has not been systematically assessed using randomised controlled trials. In this study, we aimed to systematically assess randomised controlled trials, with at least 5 years of follow-up, on bariatric surgery in patients with T2DM and BMI ≥ 25 kg/m 2 , as well as to compare different bariatric procedures. Material and Methods PubMed, SCOPUS and Web of Science were searched. We performed a network meta-analysis to evaluate the comparative effectiveness of the different procedures and MT in terms of full T2DM remission, weight loss, complications and cardiometabolic biomarkers. The quality of evidence was assessed using the Cochrane Risk of Bias Tool and CINeMA. ResultsWe included 11 primary studies. Laparoscopic one-anastomosis gastric bypass (LOAGB) was found to be one of the most effective treatments for full remission of T2DM (I 2 = 0, inconsistency p value = 0.9223). Biliopancreatic diversion without duodenal switch was found to be more effective than laparoscopic Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding regarding percent total cholesterol and low-density lipoprotein change. Regarding percent high-density lipoprotein and weight change, all analysed surgical treatments were shown to be more effective than MT. The confidence rating in our results was overall moderate, but most studies had high risk of performance and detection bias. Conclusion Bariatric surgery seems to be effective for T2DM remission. LOAGB appears to be a good option in this context, and a possible alternative to laparoscopic duodenal switch, but the included primary studies in our review are not sufficiently powered to establish a more definitive conclusion. More studies with longer follow-up times are needed to comprehensively assess bariatric surgery in T2DM.

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Section: Discussionmentioning

confidence: 99%

Comparative Effectiveness of Bariatric Surgeries in Patients with Type 2 Diabetes Mellitus and BMI ≥ 25 kg/m2: a Systematic Review and Network Meta-Analysis

et al. 2021

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“…4B). Of 3 studies, 23,26,27 no difference in reoperation rate (OR = 0.58, 95% CI: 0.14, 2.43, I 2 = 77%) (Fig. 4C) was observed between the 2 groups.…”

Section: Perioperative Outcomesmentioning

confidence: 91%

Single Versus Double Anastomosis Duodenal Switch in the Management of Obesity: A Meta-analysis and Systematic Review

Nakanishi

Matar

Vahibe

et al. 2022

Surgical Laparoscopy, Endoscopy &Amp; Percutaneous Techniques

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Background: Biliopancreatic diversion with duodenal switch (BPD-DS) is an effective yet technically challenging bariatric surgery with many complications. Alternatively, single anastomosis duodenalileal bypass with sleeve gastrectomy (SADI-S) was recently introduced as a simplified bariatric procedure. This meta-analysis aimed to assess the safety and efficacy of SADI-S compared with BPD-DS in the management of patients with obesity.Methods: Cochrane, Embase, PubMed, Scopus, and Web of Science were searched for articles from their inception to May 2022 by 2 independent reviewers using the Preferred Reporting Items for Systematic Reviews and Meta-analysis system. The review was registered prospectively with PROSPERO (CRD42022333521).Results: From 123 studies screened, 6 studies met the eligibility criteria, with a total of 1847 patients with obesity undergoing either SADI-S (n = 818) or BPD-DS (n = 1029). Preoperative body mass index was similar between the 2 groups, and the BPD-DS group had a greater % excess body mass index loss (EBMIL) (MD = −10.16%, 95% confidence interval: −11.80, −8.51, I 2 = 0%) at 2 years compared with the SADI-S group. There was no difference observed in preoperative comorbidities and remission, including diabetes, hypertension, and dyslipidemia between SADI-S and BPD-DS cohorts. Compared with BPD-DS, SADI-S had shorter hospital stays (MD = −1.36 d, 95% CI: −2.39, −0.33, I 2 = 86%), and fewer long-term ( > 30 d) complications (OR = 0.56, 95% CI: 0.42, 0.74, I 2 = 20%). Conversely, among nutritional deficiency outcomes, the SADI-S group had few patients with abnormal vitamin D (OR = 0.51, 95% CI: 0.36, 0.72, I 2 = 0%) values than the BPD-DS group.Conclusions: SADI-S has shown to be a possible alternative treatment option to BPD-DS in managing patients with obesity. Despite the promising results, further randomized controlled studies with more extended follow-up periods are necessary to ascertain the safety and efficacy of the treatment.

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“…Sie ist neben der Gewichtsreduktion maßgeblich für die postoperativ verbesserte Insulinwirkung und Verbesserung des Glukosestoffwechsels verantwortlich, wodurch die sehr guten Ergebnisse bezüglich einer Remission des Diabetes mellitus Typ 2 nach SADI erklärt sind 3 . Mehrere Studien konnten neben der Sicherheit des Verfahrens in der Zwischenzeit auch die Wirksamkeit in Bezug auf Gewichtsverlust und Therapie der Nebenerkrankungen zumindest mittelfristig bereits bestätigen 8 , 9 , 10 . Die aktuell publizierten 5-Jahres-Ergebnisse belegen die postulierte verringerte Komplikationsrate im Vergleich zur BPD-DS und die vergleichbare Gewichtsreduktion in den ersten Jahren mit einem Übergewichtsverlust (EWL) von mehr als 70% nach 24 Monaten 10 .…”

Section: Single Anastomosis Duodeno Ileostomyunclassified

“…Mehrere Studien konnten neben der Sicherheit des Verfahrens in der Zwischenzeit auch die Wirksamkeit in Bezug auf Gewichtsverlust und Therapie der Nebenerkrankungen zumindest mittelfristig bereits bestätigen 8 , 9 , 10 . Die aktuell publizierten 5-Jahres-Ergebnisse belegen die postulierte verringerte Komplikationsrate im Vergleich zur BPD-DS und die vergleichbare Gewichtsreduktion in den ersten Jahren mit einem Übergewichtsverlust (EWL) von mehr als 70% nach 24 Monaten 10 . Nach 5 Jahren war der EWL nur wenig niedriger als nach BPD-DS.…”

Section: Single Anastomosis Duodeno Ileostomyunclassified

Der Stellenwert neuerer Verfahren in der Adipositaschirurgie (SADI, SASI und Co.)

Gärtner¹,

Schöttler²,

Popp³

2022

Allgemein- und Viszeralchirurgie up2date

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Die Adipositaschirurgie bietet die effektivste Therapieoption für die Adipositas und ihre Nebenerkrankungen. Von Beginn an unterlag diese Chirurgie einem steten Wandel. Durch Modifikationen etablierter OP-Methoden wollen die neueren Verfahren die Invasivität und die unerwünschten Wirkungen reduzieren. Der folgende Beitrag zeigt, inwieweit dies gelingt und welche Verfahren das Potenzial zum Standardverfahren haben.

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SADI-S 250 vs Roux-en-Y Duodenal Switch (RY-DS): Results of 5-Year Observational Study

Cited by 47 publications

References 29 publications

Comparative Effectiveness of Bariatric Surgeries in Patients with Type 2 Diabetes Mellitus and BMI ≥ 25 kg/m2: a Systematic Review and Network Meta-Analysis

Comparative Effectiveness of Bariatric Surgeries in Patients with Type 2 Diabetes Mellitus and BMI ≥ 25 kg/m2: a Systematic Review and Network Meta-Analysis

Single Versus Double Anastomosis Duodenal Switch in the Management of Obesity: A Meta-analysis and Systematic Review

Der Stellenwert neuerer Verfahren in der Adipositaschirurgie (SADI, SASI und Co.)

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