Starting a Medical Technology Venture as a Young Academic Innovator or Student Entrepreneur

Manbachi, Amir; Kreamer-Tonin, Katlin; Walch, Philipp; Gamo, Nao J; Khoshakhlagh, Parastoo; Zhang, Yu Shrike; Montague, Charles; Acharya, Soumyadipta; Logsdon, Elizabeth A.; Allen, Robert H.; Durr, Nicholas J.; Luciano, Mark; Theodore, Nicholas; Brem, Henry; Yazdi, Youseph

doi:10.1007/s10439-017-1938-x

Cited by 18 publications

(22 citation statements)

References 26 publications

(17 reference statements)

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“…Entrepreneurship courses, funding practical researches and development of biomedical science and technology parks will be useful tools bridging this old gap. [31323334]…”

Section: Discussionmentioning

confidence: 99%

Altmetric analysis of contemporary Iranian Medical Journals

Kolahi¹,

Khazaei

Bidram

et al. 2019

Int J Prev Med

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Background: Altmetrics is a newly emerging scholarly tool measuring online attention surrounding scientific research outputs. With respect to increasing demand of disseminating research findings on the World Wide Web, this study aims to analyze the altmetric statues of Iranian medical journals. Methods: On February 27, 2019, the list of Iranian medical journals extracted from http://journals.research.ac.ir/ and consequently altmetric data token out from Altmetric database (Altmetric LLP, London, UK). The science mapping done via keyword co-occurrence, co-citation and co-authorship, network analysis using the VOSviewer. The Pearson coefficient was then employed for the correlation analysis using R. Results: Among a total of 104 journals, 7518 articles were mentioned in Altmetric data resources (Mean: 72.28, Confidence Level (95.0%): 16.8), total mentions were 27577 (Mean: 265.16, Confidence Level (95.0%): 79.9). Considering the total mentions of articles, International Journal of Preventive Medicine achieved the first rank, followed by Journal of Research in Medical Sciences and Iranian Journal of Public Health . Notably, Twitter was the most popular altmetric resource followed by Facebook and news outlets. Tweets were generally from the United States and United Kingdom. Among top 5% popular Iranian medical articles multiple sclerosis, cancer, and anxiety was hot topics. Conclusions: Iranian biomedical journal editors and research scientists needs to be more dynamic in World Wide Web using social media, post-publication peer review tools, Stack Exchange (Q and A) sites, research highlight tools, Wikipedia, and etc. In spite, more attention to the concept of evidence-based policymaking, by Iranian government along with the health policymakers seems necessary.

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“…Entrepreneurship courses, funding practical researches and development of biomedical science and technology parks will be useful tools bridging this old gap. [31323334]…”

Section: Discussionmentioning

confidence: 99%

Altmetric analysis of contemporary Iranian Medical Journals

Kolahi¹,

Khazaei

Bidram

et al. 2019

Int J Prev Med

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“…β-TCP is considered to be an important bone graft material in clinical use due to its solubility, excellent biocompatibility, osteoconductivity and ability to provide a temporary framework for bone remodeling [18–20]. However, the use of β-TCP is limited by its inherent lack of osteoinductivity, the ability to induce new bone formation.…”

Section: Discussionmentioning

confidence: 99%

3D-printed β-TCP bone tissue engineering scaffolds: Effects of chemistry on in vivo biological properties in a rabbit tibia model

et al. 2018

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In this study the effects of 3D printed SiO2 and ZnO doped tricalcium phosphate (TCP) scaffolds with interconnected pores were evaluated on the in vivo bone formation and healing properties of a rabbit tibial defect model. Pure and doped TCP scaffolds were fabricated by a ceramic powder-based 3D printing technique and implanted into critical sized rabbit tibial defects for up to 4 months. In vivo bone regeneration was evaluated using chronological radiological examination, histological evaluations, SEM micrographs and fluorochrome labeling studies. Radiograph results showed that Si/Zn doped samples had slower degradation kinetics than the pure TCP samples. 3D printing of TCP scaffolds improved bone formation. The addition of dopants in the TCP scaffolds improved osteogenic capabilities when compared to the pure scaffolds. In summary, our findings indicate that addition of dopants to the TCP scaffolds enhanced bone formation and in turn leading to accelerated healing.

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“…The thickness of the shear layers was measured from the PIV data of the vorticity and velocity fields figure. Further details of PIV measurements can be found in Hatoum et al [21-27]. …”

Section: Methodsmentioning

confidence: 99%

Reduction of Pressure Gradient and Turbulence Using Vortex Generators in Prosthetic Heart Valves

Hatoum

Dasi

2018

Ann Biomed Eng

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Blood damage and platelet activation are inherent problems with present day bi-leaflet mechanical heart valve designs. Passive flow control through different arrangements of vortex generators (VG) as means of improving pressure gradients and reducing turbulence are investigated. Rectangular VG arrays were mounted on the downstream surfaces of a 23 mm 3D printed mechanical valve. The effect of VGs on the resulting flow structures were assessed under pulsatile physiological flow conditions where high resolution particle image velocimetry measurement was performed. The co-rotating VGs showed lower Reynolds shear stresses and improved pressure gradients (PG) compared with the counter-rotating ones and the no-VG control one (that showed higher turbulence). RSS was found 38.13 ± 0.89, 12.95 ± 0.32, 15.75 ± 0.71, 24.54 ± 0.84 and 16.33 ± 0.58 Pa for the control, co-rotating VGs, 8 counter-rotating VGs, 4 far-spaced VGs and 4 closely-spaced VGs, respectively. PG of 10.45 ± 0.94 mmHg was obtained with co-rotating VGs and the difference was significant compared with the other configurations (control 14.88 ± 0.4 mmHg; 8 counter-rotating VGs 13.76 ± 0.51 mmHg; 4 far-spaced VGs 13.84 ± 0.09 mmHg; and 4 closely-spaced VGs 15.37 ± 0.16 mmHg). Co-rotating VGs for this application induce a more delayed flow separation and a more homogenized and streamlined transition of flow compared with the counter-rotating VGs. Passive flow control techniques deployed on BHMVs is potentially beneficial as significant control of flow at small length scales without inducing large-scale design modifications of the valve.

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Starting a Medical Technology Venture as a Young Academic Innovator or Student Entrepreneur

Cited by 18 publications

References 26 publications

Altmetric analysis of contemporary Iranian Medical Journals

Altmetric analysis of contemporary Iranian Medical Journals

3D-printed β-TCP bone tissue engineering scaffolds: Effects of chemistry on in vivo biological properties in a rabbit tibia model

Reduction of Pressure Gradient and Turbulence Using Vortex Generators in Prosthetic Heart Valves

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