Staging of Prostate Cancer Using 3-Dimensional Transrectal Ultrasound Images: A Pilot Study

Garg, Sudhanshu; Fortling, Bjørn; Chadwick, D. J.; Robinson, Mary C.; Hamdy, Freddie C.

doi:10.1016/s0022-5347(05)68276-6

Cited by 32 publications

(7 citation statements)

References 16 publications

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“…To our knowledge we are the first group to evaluate 3D-TRUS for staging prostate cancer in a large group of patients. In a pilot study on 36 patients with newly diagnosed clinically localized prostate cancer, Garg et al [13] used 3D-TRUS with a conventional scanner and no power Doppler US enhancement. They found that 3D-TRUS had an overall staging accuracy of 94%.…”

Section: Discussionmentioning

confidence: 99%

The value of three‐dimensional transrectal ultrasonography in staging prostate cancer

et al. 2007

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RESULTSPathological staging of specimens showed extracapsular extension in 69 patients, of whom 53 had pathological capsular perforation and 16 had seminal vesicle invasion. 3D-TRUS identified 58 patients with sites of extracapsular extension with 84% sensitivity, 96% specificity, 94% positive predictive value, 91% negative predictive value and an overall accuracy of 92%. Of the 16 patients with seminal vesicle invasion 14 were identified correctly on 3D-TRUS. Overall the 3D-TRUS staging sensitivity was 84%, specificity 96%, positive predictive value 93%, negative predictive value 91% and accuracy 91%. CONCLUSIONS3D-TRUS seems to be an accurate technique for staging localized prostate cancer. If 3D-TRUS indicates locally advanced disease, the probability of capsular perforation or seminal vesicle invasion is very high.

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Section: Discussionmentioning

confidence: 99%

The value of three‐dimensional transrectal ultrasonography in staging prostate cancer

et al. 2007

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“…Recently, in a very limited series of 9 patients, the diagnostic accuracy of 3-dimensional TRUS in predicting extraprostatic extension was reported to be superior to that of conventional TRUS. 27 Currently, such variables as the PSA value and Gleason score are used to predict pathologic stage. 6À9 Partin et al 6 reported that the combination of PSA, Gleason score, and clinical stage predicted final pathologic stage best, compared with each variable alone.…”

Section: Discussionmentioning

confidence: 99%

Role of systematic ultrasound‐guided staging biopsies in predicting extraprostatic extension and seminal vesicle invasion in men with prostate cancer

Okihara

Kamoi

Lane

et al. 2002

J of Clinical Ultrasound

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Staging biopsies can reliably sample extraprostatic tissue, including the seminal vesicles and neurovascular bundles. Positive staging biopsy results can aid in the selection of treatment options and in the prediction of outcome for individual patients by providing definitive histologic confirmation of locally advanced disease. Conventional predictive variables for staging can be applied when the results of staging biopsies are negative.

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“…In ei ner Pi lot stu die an 36 Pa ti en ten mit neu di ag nos ti zier ten kli nisch lo kal begrenz ten Pros ta ta kar zi nom konn ten Garg et al [29] eine Sta ging ge nau ig keit von 94 nach wei sen. In ih rer Stu die lag die Sen si tivi tät für das lo ka le Sta ging bei 80 und die Spe zi fi tät bei 96 mit ei nem po si tiven Vor her sa ge wert von 90 und ne gati ven Vor her sa ge wert von 96 in der Erken nung der Kap sel über schrei tung.…”

Section: Trans Rek Tale Drei DI Men Sio Na Le So No Gra Phieunclassified

Innovative Diagnostik in der Früherkennung und beim Staging des lokalisierten Prostatakarzinoms

Rinnab

Küfer

Hautmann

et al. 2005

Urologe

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Prostate cancer is the most common malignancy in males. Men aged 50 years and older are recommended to undergo an annual digital rectal examination (DRE) and determination of prostate-specific antigen (PSA) in serum for early detection. Fortunately, disease-specific mortality continues to decline as a result of advances in screening, staging, and patient awareness. However, about 30% of men with a clinically organ-confined disease show evidence of extracapsular extension or seminal vesicle invasion on pathological analysis. Consequently, there is a need for more accurate diagnostic tools for planning tailored treatment. A variety of modern imaging techniques has been implemented in an attempt to obtain more precise staging, thereby allowing for more detailed counseling, and instituting optimum therapy. This review highlights developments in prostate cancer imaging that may improve staging and treatment planning for prostate cancer patients.

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Staging of Prostate Cancer Using 3-Dimensional Transrectal Ultrasound Images: A Pilot Study

Cited by 32 publications

References 16 publications

The value of three‐dimensional transrectal ultrasonography in staging prostate cancer

The value of three‐dimensional transrectal ultrasonography in staging prostate cancer

Role of systematic ultrasound‐guided staging biopsies in predicting extraprostatic extension and seminal vesicle invasion in men with prostate cancer

Innovative Diagnostik in der Früherkennung und beim Staging des lokalisierten Prostatakarzinoms

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