Squamous metaplasia and squamous-cell carcinoma of the rectosigmoid

Cabrera, Aurelio; Pickren, John W.

doi:10.1007/bf02617142

Cited by 36 publications

(11 citation statements)

References 12 publications

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“…There is no example in the histological records of St Mark's Hospital. The only case in the literature which may be authentic (Cabrera and Pickren, 1967) did not exclude the possibility of upward extension of the anal squamous epithelium into the rectum.…”

Section: Discussionmentioning

confidence: 92%

Squamous carcinoma of the colorectum and its genesis

Williams

Blackshaw

Morson

1979

The Journal of Pathology

216

168

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A case of pure aquamous carcinoma of the rectum is presented, and the literature reviewed. Squamous carcinomas of the colorectum are rare tumours which have clinicopathological features in common with adenocarcinomas. Evidence is presented to support the proposal that most tumours of the large intestine that consist partly or completely of squamous elements arise from areas of squamous differentiation in pre-existing adenomas. The pathogenesis of squamous carcinoma and adenosquamous carcinoma appears to be similar to that of adenocarcinoma.

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Section: Discussionmentioning

confidence: 92%

Squamous carcinoma of the colorectum and its genesis

Williams

Blackshaw

Morson

1979

The Journal of Pathology

216

168

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“…Some of these cases developed carcinoma or dysplasia 1, 2, 6, 8 , indicating that squamous metaplasia of the colon is a precursor to carcinoma. The rarity of premalignant cases of colonic squamous metaplasia in the literature may reflect how difficult it is to identify pre-neoplastic metaplasia during conventional endoscopy.…”

Section: Discussionmentioning

confidence: 99%

Confocal endomicroscopic evaluation of colorectal squamous metaplasia and dysplasia in ulcerative colitis

Lord¹,

Upton

Hwang

2011

Gastrointestinal Endoscopy

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“…11 It could be a proliferation of uncommitted reserve or basal cells after mucosal injury. 16,17 The tumor could also be derived from a persistent embryonic nest of committed or uncommitted ectodermal cells, which may remain in an ectopic site after embryogenesis. [12][13][14][15] Colorectal SCC could arise from squamous metaplasia secondary to chronic injury, such as squamous carcinoma of the bronchus, closely related to metaplasia.…”

Section: Discussionmentioning

confidence: 99%