2011
DOI: 10.1007/s00467-011-1910-1
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Squamous cysts arising from segmental renal dysplasia

Abstract: We further proved, with fluorescent in situ hybridization (FISH), the negativity of 12p amplification in this lesion, supporting the notion that this lesion is not intrarenal teratomatous in nature.

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Cited by 3 publications
(2 citation statements)
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“…The hallmark feature of SRD is the presence of ureteral duplication (duplex kidney), which is usually seen in neonates or children, and only rarely diagnosed in adulthood. [5][6][7] In approximately 25 reported adult cases with segmental dysplasia, patients had vesicoureteral reflux, ectopic ureter(s) with duplex and triplex kidney, ureteropelvic obstruction, hydroureter, voiding dysfunction, repeat urinary tract infections, abdominal pain, and genital anomalies. 5,7,8 Morphologically SRD is characterized by distorted cysts of various sizes lined by flattened to cuboidal epithelium, immature collecting ducts surrounded by fibromuscular collars and undifferentiated mesenchyme, blastema, islands of cartilage, and abortive glomerular structures.…”
Section: Discussionmentioning
confidence: 99%
“…The hallmark feature of SRD is the presence of ureteral duplication (duplex kidney), which is usually seen in neonates or children, and only rarely diagnosed in adulthood. [5][6][7] In approximately 25 reported adult cases with segmental dysplasia, patients had vesicoureteral reflux, ectopic ureter(s) with duplex and triplex kidney, ureteropelvic obstruction, hydroureter, voiding dysfunction, repeat urinary tract infections, abdominal pain, and genital anomalies. 5,7,8 Morphologically SRD is characterized by distorted cysts of various sizes lined by flattened to cuboidal epithelium, immature collecting ducts surrounded by fibromuscular collars and undifferentiated mesenchyme, blastema, islands of cartilage, and abortive glomerular structures.…”
Section: Discussionmentioning
confidence: 99%
“…To our knowledge, only 37 pediatric cases and 2 adult cases of segmental MCDK have been reported worldwide. [1][2][3]7,10,11,14,[22][23][24][25] Among those, 26 patients (66.7%) underwent partial or total resection of the affected segment, and only 13 patients (33.3%) underwent conservative treatment, with the longest follow-up period being 84 months. 1 This high prevalence of resection, such as nephrectomy or partial nephrectomy, was based on concerns about complications of MCDK, such as malignant transformation and development of hypertension.…”
Section: Complicationsmentioning
confidence: 99%