Squamous Cell Carcinoma of Mandible with Unusual Clinical Presentation

Abstract

Squamous cell carcinoma (SCC) is commonly seen malignant epithelial neoplasm of the oral cavity, which is characterized by variable clinical manifestations. It arises from dysplastic squamous epithelium. Majority of the spread of oral SCC (OSCC) to mandibular bone occurs by direct infiltration of the tumour through alveolar ridge or lingual cortical plate. Only 6% of the OSCC present with primary tumour; hence, a comprehensive whole body imaging needs to be done for ruling out primary tumour anywhere else in the body along with a proper clinical examination. Here, we present an unusual case of long-standing aggressive primary malignancy with unusual clinical presentation in mandibular anterior region associated with chronic tobacco chewing in a 65-year-old male patient.

Reconstruction of the surgical defect by two flaps in a case of oral squamous cell carcinoma of the lower right gingivabuccal sulcus: A case report

“…Oral SCC is the commonest malignant neoplasm of oral and maxillofacial carcinoma; it is aggressive compared to other carcinomas (Verma et al, 2021). Gingival Squamous Cell Carcinoma frequently involves the mandible more than the maxilla (Acharya et al, 2019).…”

“…SCC is the most common malignancy of the oral mucosa. It can present in the clinical forms of non-healing ulcers, premalignant lesions or conditions, metastatic tumours, or deep fungal infections (Verma et al, 2021).…”