Sprayable antibacterial Persian gum-silver nanoparticle dressing for wound healing acceleration

Sprayable Bioactive Dressings for Skin Wounds: Recent Developments and Future Prospects

“…In situ formation of fibers and films obtained by solvent evaporation is yet another approach to spray wound dressings. The technique consists of solubilizing the polymer, either synthetic [51][52][53][54][55] or natural [56,57], in a suitable solvent and then spraying this solution. When the solvent evaporates, the polymer forms a protective film or, if the solution blow spinning (SBS) technique is used, a fibrillar mesh.…”

“…Among the compounds used, silver nanoparticles are the most investigated. Used in several studies, they provided the wound dressings with antimicrobial action against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa [26,27,43,56]. McLaughlin et al [74] developed a collagen I-based spray formulation containing silver nanoparticles modified with AMP LL37 to act as an antimicrobial and antibiofilm barrier with reduced side effects.…”

Metal-coordination synthesis of a natural injectable photoactive hydrogel with antibacterial and blood-aggregating functions for cancer thermotherapy and mild-heating wound repair

“…15,16 Farsi gum (FG) is an exudate polysaccharide obtained from the trunk and branches of Amygdalus scoparia Spach, which is less studied despite its high potential for biomedical application due to its low-cost, safety, and high-water absorption. [17][18][19][20][21][22] Sodium alginate (Alg), an anionic polysaccharide, is another widely used natural polymer for the preparation of hydrogels due to its biocompatibility, low toxicity, and facile gel formation ability. 23,24 Interestingly, these two polymers can present an enhanced hemostatic capacity through their highwater absorbing capacity and negative charge, which can induce coagulation by initiating the autoactivation of the coagulation factor XII.…”

Avian Egg: A Multifaceted Biomaterial for Tissue Engineering

“…However, the lack of adequate and proper donor organs and the inability of prostheses and mechanical devices to restore a patient’s normal life highlight the need for alternatives. − Tissue engineering (TE) has emerged as an attractive alternative for treating tissue malfunctions. − TE is at the interface of materials science, chemistry, bioengineering, and cell biology. Using principles from these fields, TE aims to develop biological substitutes to maintain, restore, or improve tissue function by combining a scaffold, cells, and biomolecules. ,, Biomaterials play a vital role in TE because they can provide cells with a microenvironment mimicking their native physiological niche, thereby enabling tissue regeneration. − Biomaterials can be created from synthetic or naturally occurring sources, such as seashells or eggs. Among various sources of materials, those that are naturally derived can recapitulate extracellular matrix (ECM) elements such as cell binding sites, which can ultimately influence the cellular behaviors (e.g., spreading, migration, differentiation) needed for tissue growth both in vitro and in vivo . − …”

“…Using principles from these fields, TE aims to develop biological substitutes to maintain, restore, or improve tissue function by combining a scaffold, cells, and biomolecules. 1,10,11 Biomaterials play a vital role in TE because they can provide cells with a microenvironment mimicking their native physiological niche, thereby enabling tissue regeneration. 12−14 Biomaterials can be created from synthetic or naturally occurring sources, such as seashells or eggs.…”