2019
DOI: 10.1016/j.ejpb.2019.07.023
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Spray dried curcumin loaded nanoparticles for antimicrobial photodynamic therapy

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Cited by 37 publications
(19 citation statements)
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“…For this, adaptogenic herbs from the traditional system of medicine like Ayurvedic and Unani may be useful as rational formulation. Nano-spray suspension coated with a stable polymer and suspending agents along-with receptor-ligand could stabilize the entrapped Phyto-pharmacological agents like curcumin-nano-formulation ( Preis et al ., 2019 ; Taki et al ., 2016 ) for longer duration avoiding the pharmacokinetic failure. The application of nano-spray might be useful also to contain the infection for spreading further, when mild to moderate symptoms would arise by augmenting the cell surface receptor activation ( Furin and TMPRSS2 ).…”
Section: Discussionmentioning
confidence: 99%
“…For this, adaptogenic herbs from the traditional system of medicine like Ayurvedic and Unani may be useful as rational formulation. Nano-spray suspension coated with a stable polymer and suspending agents along-with receptor-ligand could stabilize the entrapped Phyto-pharmacological agents like curcumin-nano-formulation ( Preis et al ., 2019 ; Taki et al ., 2016 ) for longer duration avoiding the pharmacokinetic failure. The application of nano-spray might be useful also to contain the infection for spreading further, when mild to moderate symptoms would arise by augmenting the cell surface receptor activation ( Furin and TMPRSS2 ).…”
Section: Discussionmentioning
confidence: 99%
“…This plays an important role in membrane integrity and thus the ability to successfully deliver the active ingredient. Curcumin was chosen as it is a commonly used photosensitizer with a well-known impact [ 14 , 17 , 30 ]. Additionally, the suitability of two different nebulisation techniques, vibrating-mesh and air-jet, was tested and compared for the nebulisation of liposomes in small amounts.…”
Section: Introductionmentioning
confidence: 99%
“…Since nanoparticles exhibited mechanisms leading to higher permeability by directly interacting with the bacterial cell wall and disrupting its three-dimensional organization, thereby increasing the uptake of photosensitizer (curcumin), and enhancing the aPDT efficacy. [16] . Pourhajibagher M et al indicated the antibacterial properties of nano-curcumin (nCur) reinforced with aPDT.…”
Section: Dear Editormentioning
confidence: 99%