Sporotrichosis

Lurie, H. I.

doi:10.1007/978-3-642-80570-7_14

Cited by 5 publications

(3 citation statements)

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“…273 -275 This organism is found in nature growing as a saprophyte on plants, trees, wood timbers, sphagnum moss, and other plant materials. 276 Sporotrichosis is worldwide in temperate as well as tropical areas, but most documented cases have originated from the United States, South Africa, Mexico, and South America, Most infections are nonpulmonary, and result from accidental cutaneous inoculation of the fungus growing on plant materials such as thorns. The mycosis is considered to be an occupational disease, occurring most often in farmers, gardeners, forestry workers, florists, and others who are frequently exposed to plants.…”

Section: Sporotrichosismentioning

confidence: 99%

Fungal Infections

Haque

McGinnis

2008

Dail and Hammar’s Pulmonary Pathology

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The incidence of invasive fungal infections has increased dramatically over the past two decades, mostly due to an increase in the number of immunocompromised patients. l -4 Patients who undergo chemotherapy for a variety of diseases, patients with organ transplants, and patients with the acquired immune deficiency syndrome have contributed most to the increase in fungal infections. s The actual incidence of invasive fungal infections in transplant patients ranges from 15% to 25% in bone marrow transplant recipients to 5% to 42% in solid organ transplant recipients. 6 ,7 The most frequently encountered are Aspergillus species, followed by Cryptococcus and Candida species. Fungal infections are also associated with a higher mortality than either bacterial or viral infections in these patient popUlations. This is because of the limited number of available therapies, dose-limiting toxicities of the antifungal drugs, fewer symptoms due to lack of inflammatory response, and the lack of sensitive tests to aid in the diagnosis of invasive fungal infections. I A study of patients with fungal infections admitted to a university-affiliated hospital indicated that communityacquired infections are becoming a serious problem; 67% of the 140 patients had community-acquired fungal pneumonia. 8 There is also an increase in nosocomial fungal infections.9Fungi are eukaryotic, unicellular to multicellular organisms that have chitinous cell walls, and reproduce asexually, sexually, or both ways. Fungal cells are larger and genomically more complex than bacteria. Their cell wall contains polysaccharides, proteins, and sugars, and their antigens are rich in complex polysaccharides and glycoproteins. Plasma membranes of fungi contain ergosterol, which is the primary target for antifungals such as amphotericin B. Although there are more than 1.3 million fungal species in the environment, only about 150 are known to be pathogenic to humans. For detailed taxonomy of the fungi, several texts are available. W-12 The virulence factors of fungi resemble those of bacteria, such as possession of a capsule, adhesion molecules, toxins, free radicals, etc.

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Section: Sporotrichosismentioning

confidence: 99%

Fungal Infections

Haque

McGinnis

2008

Dail and Hammar’s Pulmonary Pathology

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“…Lurie y Pinkus han sugerido que el cuerpo asteroide esporotricósico se presentarla en situaciones de mayor resistencia al hongo y que cuando se ve, las formas clínicas serían más benignas (29,46). Estos conceptos concuerdan con su presencia en 36 de 39 casos en Australia (301, 37 de los cuales eran de la forma fija o localizada, considerada como de reinfección, con mayor resistencia del huésped (47,47 A).…”

Section: Significado Del Cuerpo Asteroide Esporotricosicounclassified

“…En esta epidemia, el CAE se observó en el examen directo del pus o en los cortes del pus fijados en formo1 e incluídos en parafina, o en las 14 biopsias estudiadas inicialmente (49) y en la mayoría de las 63 biopsias estudiadas por Lurie, en las cuales vio 17 CAE en 32 nódulos primarios y 22 en 31 nódulos secundarios (36). El mismo autor sugirió que el material radiado más prominente se ve en la enfermedad menos severa: una lesión solitaria de un año de evolución y una lesión recurrente de 7 meses de evolución, que había sido tratada en forma inadecuada 10 años antes (46); los cuerpos asteroides pequeños, con mínimo material radiante, los vi6 en nódulos secundarios o en pacientes con lesiones múltiples o con lesiones óseas o viscerales (10,46). Pero, en las formas pulmonares, meníngeas, diseminadas, de baja resistensia, se han visto numerosos cuerpos asteroides en conglomerados (31,32).…”

Section: Significado Del Cuerpo Asteroide Esporotricosicounclassified