Splénomégalie et pseudo-tumeur splénique d'origine tuberculeuse : six nouvelles observations

Rhazal, F.; Lahlou, M. K.; Benamer, S.; Daghri, J.M.; Essadel, E.; Mohammadine, E.; Taghy, A.; Chad, B.; Belmahi, A.

doi:10.1016/j.anchir.2004.03.011

Cited by 8 publications

(10 citation statements)

References 5 publications

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“…The initial presentation as pyrexia of unknown origin is characteristic of splenic TB in literature [7, 17]. Apart from fever which is present in majority of patients with splenic TB, other modes of presentation reported include fatigue and weight loss, splenomegaly, [18] splenic rupture, [19] hypersplenism, portal hypertension with and without gastrointestinal bleed, and fulminant forms involving rapid progression [18]. Hematologic abnormalities include reduced cell counts but cases of polycythaemia have also been reported [20].…”

Section: Discussionmentioning

confidence: 99%

Isolated splenic tuberculosis with subsequent paradoxical deterioration: a case report

et al. 2017

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BackgroundIsolated tuberculosis of the spleen has been described occasionally in literature, mostly in immunosuppressed individuals with various risk factors. Sequestration in the spleen makes such Mycobacterium tuberculosis infection difficult to diagnose. This report describes an extremely rare case of isolated splenic tuberculosis in an immunocompetent individual.Case presentationA 26 year old Kenyan male presented with pyrexia of unknown origin, with negative screening tests for bacterial, fungal and parasitic infections. Ziehl–Neelsen staining and GeneXpert tests were negative for M. tuberculosis. Diagnosis of isolated splenic tuberculosis was made on core biopsy of the spleen. The patient initially worsened upon treatment with antituberculous medication attributable to the ‘Paradoxical Reaction’ phenomenon, before making full recovery.ConclusionsThis case highlights the need to continuously be on the lookout for tuberculosis especially in unusual presentations, including subsequent paradoxical reaction which may be encountered.Electronic supplementary materialThe online version of this article (doi:10.1186/s13104-017-2483-2) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

Isolated splenic tuberculosis with subsequent paradoxical deterioration: a case report

et al. 2017

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“…Clinically, the most common symptoms that patients present with are fever (82.3%), fatigue and weight loss (44.12%), and splenomegaly (13.2–100%). 7 , 11 Rarely, patients can be asymptomatic and their diagnosis is delayed. Pain is an uncommon symptom.…”

Section: Discussionmentioning

confidence: 99%

“… 6 Other presentations include splenic rupture, 4 hypersplenism, portal hypertension with and without gastrointestinal bleed, 11 and fulminant form involving rapid progression of fever, cachexia, hemorrhage and sepsis. 11 Splenic tuberculosis patients can also present with hematologic abnormalities. Usually they are cytopenic, but cases of polycythemia have also been reported.…”

Section: Discussionmentioning

confidence: 99%

“…On computed tomography, tuberculomas appear as non-enhancing homogenous hypodensities and homogenous splenomegaly can also be appreciated. 11 , 12 Fine needle aspiration cytology is a valuable too, with sensitivity of 88% and specificity of up to 100%. 10 , 11 It should be considered whenever splenomegaly presents with fever of unknown origin.…”

Section: Discussionmentioning

confidence: 99%

“… 11 , 12 Fine needle aspiration cytology is a valuable too, with sensitivity of 88% and specificity of up to 100%. 10 , 11 It should be considered whenever splenomegaly presents with fever of unknown origin. FNAC can also reveal caseating granulomas.…”

Section: Discussionmentioning

confidence: 99%

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