Spintronic Biochips

Freitas, P. P.; Martins, Verónica C.; Cardoso, Fabbryccio A. C. M.; Fernandes, Elisabete; Skalický, T; Castillo, José; Chícharo, Alexandre; Abal, Miguel; López‐López, Rafael; Dias, T.; Cardoso, S.

doi:10.1002/9783527698509.ch9

Cited by 6 publications

(1 citation statement)

References 71 publications

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“…Magnetic sensors have been widely used to detect magnetic nanoparticles marking target biomolecules, such as nucleoprotein, nucleic acid, and antigens by signals from magnetic particles that mark specific biomolecules [6,7]. A wide range of magnetoresistive biosensors have been developed, including Hall effect devices, giant magnetoresistive (GMR), and tunneling magnetoresistive (TMR) sensors being introduced into the biomedical field [8][9][10][11], which have advantages such as immediacy and high accuracy compared to traditional bio sensing methods. The traditional methods are time-consuming and are confined to the laboratory.…”

Section: Introductionmentioning

confidence: 99%

Biological sensing using anomalous hall effect devices

Ramesh¹,

Chou²,

Lu³

et al. 2022

Nanotechnology

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This paper outlines an approach to biological sensing involving the use of spintronic devices to sense magnetic nanoparticles attached to biological carriers. We developed an enzyme-linked immunosorbent assay (ELISA)-based Anomalous Hall Effect magnetic sensor via surface functionalization using Triethoxysilylundecanal (TESUD). The proposed sensor uses a CoFeB/MgO heterostructure with a perpendicular magnetic anisotropy. Through several sets of magnetic layer thickness, this work also explored the optimization process of ferromagnetic layer used. Our spintronics-based bio sensor is compatible with semiconductor fabrication technology and can be effectively miniaturized to integrate with semiconductor chips, which has the advantage of reduced manufacturing cost and reduced power consumption. The proposed sensor provides real-time measurement results and it is competitive to conventional biological colorimetric measurement systems in terms of accuracy and immediacy.

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