Evolution in Automatized Detection of Cells: Advances in Magnetic Microcytometers for Cancer Cells

Isolation of acute myeloid leukemia blasts from blood using a microfluidic device

“…Microfluidic devices have been successfully used for sizebased, [14][15][16][17] immune-based, 18,19 or chromatographic-based separation, 20 for cell encapsulation, [21][22][23] and also microfluidic flow cytometry. [24][25][26][27][28] Furthermore, microfluidic devices also offer high efficiency for processing complex fluids with minimal damage to the cells contained in these fluids, even the most sensitive. [29][30][31][32] For example, Ribeiro-Samy et al demonstrated the isolation of circulating tumor cells (CTCs) from whole blood using pillar structures to separate the cells of interest from the other blood cells, based on size and deformability.…”