Biological sensing using anomalous hall effect devices

Abstract

This paper outlines an approach to biological sensing involving the use of spintronic devices to sense magnetic nanoparticles attached to biological carriers. We developed an enzyme-linked immunosorbent assay (ELISA)-based Anomalous Hall Effect magnetic sensor via surface functionalization using Triethoxysilylundecanal (TESUD). The proposed sensor uses a CoFeB/MgO heterostructure with a perpendicular magnetic anisotropy. Through several sets of magnetic layer thickness, this work also explored the optimization process of ferromagnetic layer used. Our spintronics-based bio sensor is compatible with semiconductor fabrication technology and can be effectively miniaturized to integrate with semiconductor chips, which has the advantage of reduced manufacturing cost and reduced power consumption. The proposed sensor provides real-time measurement results and it is competitive to conventional biological colorimetric measurement systems in terms of accuracy and immediacy.

Perspective on nanoscale magnetic sensors using giant anomalous Hall effect in topological magnetic materials for read head application in magnetic recording

“…Because of their low 1/f noise characteristics, AHE sensors have been proposed for the detection of weak magnetic fields with low frequencies generated by small objects such as magnetic nanoparticles and cells with magnetic markers. 40 Another notable example of a magnetic sensor with small dimensions is the read head sensor (reader) used in hard disk drives (HDDs). Readers are magnetic sensors with dimensions of a few tens of nm that can playback recording patterns on magnetic media, for which tunnel magnetoresistance (TMR) devices have been used since the mid-2000s.…”