Spectrophotometric and chromatographic determination of sulfanilamides in biological fluids and pharmaceuticals

Eriochrome Black T – a New Analytical Reagent for Spectrophotometric Determination of Sulphanilamides

“…They are based on the interaction of both SA [1][2][3][4][5] and SA diazonium salts [6][7][8][9][10][11][12][13] with organic reagents leading to formation of the colored analytical forms. Even though dyes are common analytical reagents in pharmaceutical analysis, they are rarely used for SA determination.…”

Application of sulphanilamides disazo dyes with Tropaeolin O for simple, rapid and sensitive spectrophotometric assay of medicines

“…The first group of methods is based on SA determination due to own absorbance in UV spectrum range at = 245-270 nm, however, they are nonselective, because most organic compounds absorb in the same spectrum range, so these methods are suitable only for the analysis of clean substances [13]. The second group of spectrophotometric methods is based on absorbance measuring of products of coloured reaction of SA with different organic reagents, in particular, aromatic aldehydes, phenols, imines, dinitrobenzenefuroxanes [14][15][16][17][18][19][20][21][22][23][24]. However, described methods require using of organic media and they are multistage as well as nonselective and insensitive.…”

Determination of sulphathiazole and sulphanilamide by photochemically induced fluorescence and first-derivative fluorescence

“…For determining sulphanilamide, chromatographic methods have the leading position, by using mass spectrometric detection [4,5], being applied in biological fluids [6], pharmaceutical preparations [6][7][8][9] and foods [10,11]. Another techniques employed are spectrophotometry [6,12,13] with flow-injection analysis (FIA) [14] and fluorescence [15] with flow-injection analysis [16].…”

“…Another techniques employed are spectrophotometry [6,12,13] with flow-injection analysis (FIA) [14] and fluorescence [15] with flow-injection analysis [16].…”

“…Also, flow-injection analysis methods have been proposed [24]. HPLC techniques with different detection types as photometry, mass spectrometry and fluorimetry have been proposed [6,[25][26][27][28], and fluorimetric methods [29,30].…”