Specific immunoglobulins G and M in blood serum in retinoblastoma and «pseudoretinoblastoma»

Saakyan, S.V.; Катаргина, Л. А.; Krichevskaya, G. I.; Myakoshina, E. B.; Денисова, Е. В.

doi:10.17116/oftalma2017133412-16

Cited by 4 publications

(3 citation statements)

References 5 publications

(6 reference statements)

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“…First: the production of specific antibodies, especially immunoglobulin M (IgM), is low. Second, the polymerase chain reaction (PCR) assay is not sensitive enough, ranging from 35% to 83% according to different authors [12, 13].…”

Section: Introductionmentioning

confidence: 99%

Cerebral toxoplasmosis in HIV-infected patients over 2015–2018 (a case study of Russia)

et al. 2020

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Cerebral toxoplasmosis is a leading cause of the central nervous system disorders in acquired immune deficiency syndrome. This study aimed to investigate the clinical course of cerebral toxoplasmosis in human immunodeficiency virus (HIV)-infected individuals. The study included 90 HIV-infected patients with cerebral toxoplasmosis, who underwent inpatient treatment. In case of positive enzyme immunoassay, HIV infection was confirmed with the immunoblot test. The HIV-1 ribonucleic acid level was determined using the polymerase chain reaction method. The flow cytometry was used for counting CD4 (cluster of differentiation 4 cells). Pathomorphological examination included the autopsy, gross and microscopic examination of internal organs, histological and other methods. The incidence of cerebral toxoplasmosis significantly increases at the CD4 count below 100 cells/μl, P < 0.001, and at the HIV viral load above 50 copies/ml, P < 0.05. The clinical picture of cerebral toxoplasmosis included focal symptoms, cognitive impairment, toxic syndrome, mild cerebral symptoms and a meningeal symptom. Given the absence of a specific clinical picture and the absence of abnormal laboratory and instrumental findings, the cerebral toxoplasmosis needs to be diagnosed with a number diagnostic methods combined: clinical examination, laboratory testing, immunological examination, molecular genetic testing and neuroradiological imaging.

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Section: Introductionmentioning

confidence: 99%

Cerebral toxoplasmosis in HIV-infected patients over 2015–2018 (a case study of Russia)

et al. 2020

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“…In our study, we evaluated the treatment dynamics with losartan and enalapril by the MAU level, which is a prognostic factor of cardiovascular complications occurrence in patients with hypertension 28,29 . In all comparison groups, at the end of treatment, a statistically significant decrease in the MAU level was observed (p<0.05).…”

Section: Discussionmentioning

confidence: 99%

Gender-based differences in the effectiveness of antihypertensive therapy with losartan compared with enalapril

Cam¹,

Berestova

Lopatina

et al. 2021

Bangladesh J Med Sci

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Objective: Today there is a limited number of gender-based characteristics of the enalapril and losartanadministration in order to correct blood pressure in patients with arterial hypertension.The aim ofthe study was to compare the effectiveness of enalapril and losartan for blood pressure correcting inpatients with arterial hypertension (AH), depending on gender. Materials and methods: The studywas carried out in 2019 at Military Hospital 175 in Ho Chi Minh city, Vietnam. To achieve this goal,100 people were included in the study (50 females in the menopause and 50 males) with grade I-IIarterial hypertension aged 50 to 60 years. Patients with hypertension were divided into the followinggroups: group 1A – 25 males, who received enalapril 20 mg/d and 12.5 mg/d hydrochlorothiazideonce per day as antihypertensive therapy; group 1B – 25 males, who received losartan 50 mg/d andhydrochlorothiazide 12.5 mg/d once per day; group 2A – 25 females, who received enalapril 20 mg/dand hydrochlorothiazide 12.5 mg/d once per day; group 2B – 25 females, who received losartan 50mg/d and hydrochlorothiazide 12.5 mg/d once per day. The follow-up was 12 weeks. Results anddiscussion: The study showed that antihypertensive therapy with losartan is more effective in femalescompared with enalapril, as evidenced by a significant SBP decrease by 21.1% (p<0.05) at the endof treatment with losartan in females versus 18.6% (p<0.05) when using enalapril with the presenceof a statistically significant intergroup difference in the indicator (p<0.05). Conclusion: Our resultsindicate the presence of a gender difference in the antihypertensive effect of losartan and enalapril. Bangladesh Journal of Medical Science Vol.20(2) 2021 p.348-355

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“…There are few reports of autism in adults and children suffered from Neuroinfectious diseases, mainly the opportunistic infections 10,16 . The folic acid cycle is realized with three key enzymes: methylenetetrahydrofolate reductase (MTHFR), methionine synthase reductase (MTRR) and methionine synthase (MTR) 17 . This cycle functions along with the methionine cycle, and as a result the homocysteine is synthesized.…”

Section: Introductionmentioning

confidence: 99%

Features of folate cycle disorders in children with ASD

Maltsev

2020

Bangladesh J Med Sci

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Aim: to show the effect of genetically determined folate cycle deficiency in children with autism spectrum disorders (ASD). Participants: 89 children (57 boys; 32 girls, Ukraine, 2-10 years old); participants were diagnosed with ASD. The control group consisted of 34 children with ASD. Diagnostic methods:polymerase chain reaction (PCR), complex immunological research, diagnosis of infection, determination of biomarkers. Results and discussion:Hyperhomocysteinemia was revealed in 87% of cases (p <0.05; Z <Z0.05).The indicated form of immunodeficiency was noted among 91% participants in the study, while only in 27% children of the control group had a similar immunological phenotype.The serum concentration of folic acid was increased in 64%, and reduced in 21% of cases. An increase of vitamin B12 also occurred in 64%, and vitamin B6 - only in 43% of cases. Bangladesh Journal of Medical Science Vol.19(4) 2020 p.737-742

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Specific immunoglobulins G and M in blood serum in retinoblastoma and «pseudoretinoblastoma»

Cited by 4 publications

References 5 publications

Cerebral toxoplasmosis in HIV-infected patients over 2015–2018 (a case study of Russia)

Cerebral toxoplasmosis in HIV-infected patients over 2015–2018 (a case study of Russia)

Gender-based differences in the effectiveness of antihypertensive therapy with losartan compared with enalapril

Features of folate cycle disorders in children with ASD

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