Spatial Aspects of Ventricular Repolarization in Postinfarction Patients

Dilaveris, Polychronis; Gialafos, Elias; Pantazis, Antonios; Synetos, Αndreas; Triposkiadis, Filippos; Stamatelopoulos, Stamatios; Gialafos, John

doi:10.1046/j.1460-9592.2001.00157.x

Cited by 20 publications

(17 citation statements)

References 22 publications

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“…QTd results were in accordance to values reported in healthy patients [13]. JTd parameters in both groups were similar and even lower than previously reported in the medical literature [14][15][16][17].…”

Section: Resultssupporting

confidence: 90%

Normal QT dispersion in colchicine-resistant familial Mediterranean fever (FMF)

et al. 2012

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The association between familial Mediterranean fever (FMF) and subclinical cardiac disease remains controversial. The aim of the current study was to evaluate whether FMF patients, who do not respond to colchicine treatment, and thereby endure persistent inflammation, have increased QT dispersion (QTd) values. Twenty-two FMF patients and 22 age- and sex-matched control subjects were included in the study. Repolarization and QT dispersion parameters were computed from 12-lead ECG recording using designated computer software, and results of five beats were subsequently averaged. Both FMF patients and controls had similar comorbidities, similar values of average QT, average corrected QT interval length, average QTd interval, average QT corrected dispersion, QT dispersion ratio, JT dispersion (JTd), and JT corrected dispersion. In conclusion, FMF patients who were unresponsive to colchicine treatment and did not develop amyloidosis had normal QTd and JTd parameters, indicating a non-increased risk for repolarization-associated ventricular arrhythmias.

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Section: Resultssupporting

confidence: 90%

Normal QT dispersion in colchicine-resistant familial Mediterranean fever (FMF)

et al. 2012

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“…Results of QTd were similar to those reported in the medical literature for healthy subjects [13]. JTd parameters in both groups, although similar in the 2 groups, were somewhat lower than previously reported [18][19][20][21].…”

Section: Resultssupporting

confidence: 88%

QT dispersion in amyloidosis due to familial Mediterranean fever

Nussinovitch

et al. 2011

Rheumatol Int

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Cardiac amyloid deposition in FMF may cause increased QT dispersion (QTd), a marker for cardiac arrhythmias. The aim of this study was to further evaluate repolarization dispersion in familial Mediterranean fever (FMF) with amyloidosis. Findings on 12-lead electrocardiography were compared between 18 patients with FMF-amyloidosis and 18 age- and sex-matched control subjects. Repolarization and dispersion parameters were computed with designated computer software, and results of the 5 beats were subsequently averaged. There were no statistically significant differences between the groups as to average corrected QT interval length, average QTd interval, average QT corrected dispersion, or QT dispersion ratio. JT dispersion and JT corrected dispersion were also similar in both groups. In conclusion, patients with FMF-amyloidosis seem to have QT and JT dispersion parameters similar to those of healthy subjects. Future research and longer follow-ups should be conducted in order to evaluate the prognostic importance of repolarization dispersion parameters in amyloidosis of FMF.

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“…6 -11 It is of interest to note that a modest correlation between the planar QRS-T angle and the spatial QRS-T angle has been described among patient populations in whom both angles have been measured. 29,30 The widespread clinical use of other ECG risk markers such as signal-averaged ECGs and microvolt T-wave alternans has been limited in part because of the necessity of specialized equipment. The ability to easily measure the planar QRS-T angle from a standard 12-lead ECG is therefore particularly attractive and could be incorporated into automated ECG risk scoring, as has been proposed recently.…”

Section: Figurementioning

confidence: 99%

Prognostic Value and Temporal Behavior of the Planar QRS-T Angle in Patients With Nonischemic Cardiomyopathy

et al. 2008

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Background-The planar QRS-T angle can be easily obtained from standard 12-lead ECGs, but its predictive ability is not established. We sought to determine the predictive ability of the planar QRS-T angle in patients with nonischemic cardiomyopathy and to assess QRS-T angle behavior over time. Methods and Results-Baseline QRS-T angles from 455 patients in the Defibrillators in Nonischemic CardiomyopathyTreatment Evaluation (DEFINITE) trial were measured. All patients had nonischemic cardiomyopathy, New York Heart Association class I to III heart failure, and nonsustained ventricular tachycardia or frequent ventricular ectopy. The primary end point (a composite of total mortality, appropriate implantable cardioverter-defibrillator shock, or resuscitated cardiac arrest) occurred in 25 of 172 patients (14.5%) with a QRS-T angle Յ90°and in 72 of 283 patients (25.4%) with a QRS-T angle Ͼ90°(hazard ratio, 1.93; 95% confidence interval, 1.23 to 3.05; Pϭ0.002). A QRS-T angle Ͼ90°remained a significant predictor of the primary end point (Pϭ0.039) after adjustment for treatment group, age, gender, QRS duration, left bundle-branch block, left ventricular ejection fraction, New York Heart Association class III, atrial fibrillation, and diabetes mellitus. The secondary end point (total mortality) occurred in 17 of the 172 patients (9.9%) with a QRS-T angle Յ90°and in 49 of the 283 patients (17.3%) with a QRS-T angle Ͼ90°(hazard ratio, 1.79; 95% confidence interval, 1.03 to 3.10; Pϭ0.016). A sample of 152 patients with multiple follow-up ECGs was analyzed to assess temporal QRS-T angle behavior. Changes in the QRS-T angle correlated with changes in left ventricular ejection fraction and QRS duration over time (PϽ0.001). Conclusions-A planar QRS-T angle

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Spatial Aspects of Ventricular Repolarization in Postinfarction Patients

Cited by 20 publications

References 22 publications

Normal QT dispersion in colchicine-resistant familial Mediterranean fever (FMF)

Normal QT dispersion in colchicine-resistant familial Mediterranean fever (FMF)

QT dispersion in amyloidosis due to familial Mediterranean fever

Prognostic Value and Temporal Behavior of the Planar QRS-T Angle in Patients With Nonischemic Cardiomyopathy

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