Some Remarks about Tuberculosis of the Skin and Tuberculids

Lugt, L. van der

doi:10.1159/000254477

Cited by 20 publications

(6 citation statements)

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“…Previously LS was reported in association with some forms of extrapulmonary tuberculosis, especially that of the lymph nodes and bones, or both (5–10), but recently it has also been reported with pulmonary tuberculosis (11–14) and with M. avium infection (15). It has also been reported to occur after BCG vaccination (4).…”

Section: Discussionmentioning

confidence: 99%

“…It has also been reported to occur after BCG vaccination (4). These forms of extrapulmonary tuberculosis (5–10) are characterized by a high tuberculin positivity (18), indicating a greater degree of tissue hypersensitivity. Other forms of extrapulmonary disease, like miliary or meningeal tuberculosis, seen in very young children with a less effective host immune response, have never been reported to be associated with LS.…”

Section: Discussionmentioning

confidence: 99%

“…LS usually accompanies active tuberculosis, which can either be in an early or late stage. The incidence of LS is unknown, since in the past 35 years fewer than 25 cases of LS have been reported worldwide, without any racial differences (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16).…”

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confidence: 99%

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Lichen Scrofulosorum: A Rare Manifestation of a Common Disease

Thami

Kaur

Kanwar

et al. 2002

Pediatric Dermatology

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Tuberculids develop as hypersensitive immunologic reactions in the skin to an occult internal focus of tuberculosis. These eruptive lesions are due to hematogenous dissemination of bacilli in a host with a high degree of immunity against Mycobacterium tuberculosis. Although rare, these specific lesions are important diagnostic markers of tuberculosis. Lichen scrofulosorum is one of the recognized tuberculids, usually seen in children and young adults. We report three children with lichen scrofulosorum; in two children it developed during treatment of tuberculosis. The appearance of lichen scrofulosorum after initiation of treatment due to a probable increase in cell-mediated immunity is emphasized.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Lichen Scrofulosorum: A Rare Manifestation of a Common Disease

Thami

Kaur

Kanwar

et al. 2002

Pediatric Dermatology

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“…The incidence of LS is unknown, as the literature is scant. The current information about this entity is based on case reports and case series constituting small numbers (< 10) of patients 4–15 . Large series of LS and its associated tuberculous focus are lacking.…”

Section: Introductionmentioning

confidence: 99%

Lichen scrofulosorum: A prospective study of 39 patients

Singal

Bhattacharya

2005

Int J Dermatology

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“…In der Literatur der letzten Jahre finden sich geha Èuft Berichte u Èber gute Therapieerfolge nach Verabreichung von Tuberkulostatika [10,19,20,35]. Eberhartinger et al und Van der Lugt hingegen berichteten u Èber frustrierende Therapieergebnisse, ohne allerdings das Therapieregime und die Behandlungsdauer genauer zu spezifizieren [9,36]. Bei stark positiven Mantouxtest in einer Verdu Ènnung von 1 : 10 000 oder nachgewiesener Mycobacterium-tuberculosis-DNA durch PCR ist eine antituberkulo Èse 3fach Kombinationstherapie u Èber einen Zeitraum von mindestens 6 Monaten erforderlich.…”

Section: Therapieunclassified