Some Features of the Anatomical Structure of the Large Intestine of White Rats
Search citation statements
Paper Sections
Citation Types
Year Published
Publication Types
Relationship
Authors
Journals
Cited by 3 publications
References 1 publication
Morphofunctional Characteristics of Individual Organs of the Human Digestive System
Today, the growing trend of the prevalence of diseases of the digestive system is a very important issue not only in Ukraine but also around the world. This problem applies not only to practical areas of health care, but also to theoretical medicine. The study of the anatomical structure and functional state of the digestive system is the theoretical basis for the extrapolation of various pathological conditions in laboratory animals. Analysis of scientific sources showed a lack of comprehensive morphological studies of the human digestive system. The purpose of the paper was to study the features of some organs of the human digestive system in the morphological aspect by bibliographic analysis of literature. Materials and methods. This bibliographic analysis is based on published peer-reviewed articles, books, textbooks, monographs, abstracts of dissertations. For the purposes of this systematic review, literature search (concerning the study of the structure of the human digestive system) was carried out on the Internet, domestic literature sources, scientific and electronic libraries of Poltava State Medical University by the following keywords: "digestive system", "morphology", "gastrointestinal tract", "colon", "cаecum", "embryonic development of the digestive system". Results and discussion. Digestive system (Latin «systema digestorium») is a system of organs of various structures and functions formed in phylogeny, the importance of which lies in the perception, mechanical and chemical (enzymatic) processing and absorption of nutrients needed to compensate for energy and material costs in the body. Conclusion. Significant progress has been made in understanding the development of the human digestive system over the past two decades. The human digestive system is formed in phylogeny community of similar in structure and function of organs, the importance of which is the digestion of food, mechanical and enzymatic breakdown, absorption of breakdown products into the internal environment of the body and their transport to the liver. The structure of the gastric mucosa is well thought out for secretion and protection against low pH of gastric contents, which is regulated by hydrochloric acid. The pancreas, like the gland of external secretion, produces many digestive enzymes in an inactive form. Activation usually occurs in the lumen of the small intestine. The liver receives most of the nutrients absorbed through the portal vein and then uses them to synthesize many larger molecules
Morphofunctional Characteristics of Individual Organs of the Human Digestive System
Today, the growing trend of the prevalence of diseases of the digestive system is a very important issue not only in Ukraine but also around the world. This problem applies not only to practical areas of health care, but also to theoretical medicine. The study of the anatomical structure and functional state of the digestive system is the theoretical basis for the extrapolation of various pathological conditions in laboratory animals. Analysis of scientific sources showed a lack of comprehensive morphological studies of the human digestive system. The purpose of the paper was to study the features of some organs of the human digestive system in the morphological aspect by bibliographic analysis of literature. Materials and methods. This bibliographic analysis is based on published peer-reviewed articles, books, textbooks, monographs, abstracts of dissertations. For the purposes of this systematic review, literature search (concerning the study of the structure of the human digestive system) was carried out on the Internet, domestic literature sources, scientific and electronic libraries of Poltava State Medical University by the following keywords: "digestive system", "morphology", "gastrointestinal tract", "colon", "cаecum", "embryonic development of the digestive system". Results and discussion. Digestive system (Latin «systema digestorium») is a system of organs of various structures and functions formed in phylogeny, the importance of which lies in the perception, mechanical and chemical (enzymatic) processing and absorption of nutrients needed to compensate for energy and material costs in the body. Conclusion. Significant progress has been made in understanding the development of the human digestive system over the past two decades. The human digestive system is formed in phylogeny community of similar in structure and function of organs, the importance of which is the digestion of food, mechanical and enzymatic breakdown, absorption of breakdown products into the internal environment of the body and their transport to the liver. The structure of the gastric mucosa is well thought out for secretion and protection against low pH of gastric contents, which is regulated by hydrochloric acid. The pancreas, like the gland of external secretion, produces many digestive enzymes in an inactive form. Activation usually occurs in the lumen of the small intestine. The liver receives most of the nutrients absorbed through the portal vein and then uses them to synthesize many larger molecules
Introduction: The stomach and small intestine are important organs of the digestive system and, to date, they are the subject of research by morphologists, endocrinologists, immunologists, gastroenterologists, and other researchers. The aim: The paper is aimed at the study and systematization of the features of angioarchitecture of the albino rats stomach and small intestine. Materials and methods: The study based on the injection of the blood vasculature of abdominal organs of 20 albino male rats with 5% gelatin solution, colored with filtered black ink, was performed. The specimens were subject to photographing from different aspect angles in their original state, and then, after dehydration in alcohols with the transition to pure acetone, they were embedded in the epoxy. Photographing of the obtained specimens was made by a digital camera, as well as a binocular magnifier MBS-9, equipped with a digital photoattachment Sigeta DCM-900 9.0MP. Results and conclusions: The results of injecting of blood vasculature of albino rats’ gastrointestinal tract with ink mass clearly demonstrate the specific difference in the intraorganic angioarchitecture of its different regions, which depends entirely on their functional purpose in the digestive process. In the stomach, the highest concentration of blood microvessels is in its glandular part, which is explained by the increased nutrient needs of the secretory process of the gastric glands, while the mucous membrane of its fundus (pre-stomach) contains a scattered network of exchange microvessels that only promote the process of regeneration of the stratified squamous (partially keratinized) covering epithelium. In the small intestine, the typical principle of the organization of the microvasculature of its mucous membrane is somewhat modified in the duodenum, which is associated with the presence of mucous (Brunner’s) glands in it, as well as in those sites (starting from the duodenum) where the group lymph nodes (Peyer’s patches) are localized.
Introduction: The small intestine of albino rats is a transitive canal between the stomach and the cecum that is closely located from each other, reaches a length of one meter, which in comparison ratio to body weight significantly exceeds the corresponding segment in humans. The aim: The paper is aimed at thorough histological study of the wall and structure of albino rats’ small intestine mucosa. Materials and methods: 30 mature albino male rats were involved into the study. The specimens of albino rats’ small intestine, fixed in 10% neutral buffered formalin solution, have been studied. The study was carried out using conventional histological methods for obtaining serial paraffin sections stained with hematoxylin-eosin. Epoxy plastination of individual tissue samples of the small intestine was performed. Subsequently, polished thin sections were made, stained with 1% methylene blue and 1% borax solution. The obtained specimens were studied on the “Konus” light microscope equipped with Sigeta DCM-900 9.0MP digital microphoto attachment with the Biorex 3 software adapted for studies of such type. Results and conclusions: For the first time in the practice of histological study of the epithelial covering of the mucous membrane of the small intestine, attention is drawn to the specific pattern of its organization on the intestinal villi. It has been found that epithelial covering consists of alternating cluster epithelial aggregations separated by fissured depressions. Since no mentioning about them has been found in the publication, these cluster aggregations of enterocytes can be called epithelial buds of the intestinal villi. Consequently, it can be concluded that with the exception of some specific morphological features, the small intestine of albino rats is homologous to human one by its histological structure, which means that it can be used as a model for various experimental studies.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
Contact Info
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Product
Resources
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.
